| 词条 | Filamin |
| 释义 |
Filamins are a class of proteins that hold two actin filaments at large angles.[1] Filamin protein in mammals is made up of an actin-binding domain at its N-terminus that is followed by 24 immunoglobulin-like repeat modules of roughly 95 amino acids. There are two hinge regions; between repeats 15-16 and 23-24. Filamin gets cleaved at these hinge regions to generate smaller fragments of the protein. Filamin proteins include:
References1. ^{{cite journal |vauthors=Murray JT, Campbell DG, Peggie M, Mora A, Alfonso M, Cohen P |title=Identification of filamin C as a new physiological substrate of PKBα using KESTREL |journal=Biochem. J. |volume=384 |issue=Pt 3 |pages=489–94 |date=December 2004 |pmid=15461588 |pmc=1134134 |doi=10.1042/BJ20041058 |url=http://www.biochemj.org/bj/384/0489/bj3840489.htm}} External links
2 : Human proteins|Proteins |
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