词条 | Florantyrone |
释义 |
| Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 444406607 | IUPAC_name = 4-fluoranthen-8-yl-4-oxobutanoic acid | image = Florantyrone.png | tradename = | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = | routes_of_administration = | bioavailability = | protein_bound = | metabolism = | elimination_half-life = | excretion = | CAS_number_Ref = {{cascite|correct|??}} | CAS_number = 519-95-9 | ATC_prefix = none | ATC_suffix = | ATC_supplemental = | PubChem = 10617 | DrugBank_Ref = {{drugbankcite|changed|drugbank}} | DrugBank = DB08975 | UNII_Ref = {{fdacite|correct|FDA}} | UNII = UZ5LMI200P | ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}} | ChemSpiderID = 10172 | ChEMBL_Ref = {{ebicite|changed|EBI}} | ChEMBL = 2106357 | chemical_formula = | C=20 | H=14 | O=3 | molecular_weight = 302.323 g/mol | smiles = C1=CC2=C3C(=C1)C4=C(C3=CC=C2)C=C(C=C4)C(=O)CCC(=O)O | StdInChI_Ref = {{stdinchicite|changed|chemspider}} | StdInChI = 1S/C20H14O3/c21-18(9-10-19(22)23)13-7-8-14-15-5-1-3-12-4-2-6-16(20(12)15)17(14)11-13/h1-8,11H,9-10H2,(H,22,23) | StdInChIKey_Ref = {{stdinchicite|changed|chemspider}} | StdInChIKey = QOBAOSCOLAGPKI-UHFFFAOYSA-N | melting_point = 195 | solubility = soluble in methanol, ethanol, sodium carbonate }}Florantyrone (INN; also known as Fluorantyrone) is a drug used in the treatment of biliary dyskinesia. It is also known as a cholagogue and choleretic.[1] It is manufactured from fluoranthene and succinic anhydride in the presence of aluminum chloride in a nitrobenzene solution. (US PATENT 2,560,425 (1951 To Miles Lab)). References1. ^{{cite web|title=florantyrone - Compound Summary|url=https://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?q=all&cid=10617|publisher=PubChem Compound - National Center for Biotechnology Information|accessdate=15 November 2011}} {{pharma-stub}} 1 : Laxatives |
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