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词条 Florantyrone
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  1. References

{{Drugbox
| Verifiedfields = changed
| Watchedfields = changed
| verifiedrevid = 444406607
| IUPAC_name = 4-fluoranthen-8-yl-4-oxobutanoic acid
| image = Florantyrone.png
| tradename =
| pregnancy_AU =
| pregnancy_US =
| pregnancy_category =
| legal_AU =
| legal_CA =
| legal_UK =
| legal_US =
| legal_status =
| routes_of_administration =
| bioavailability =
| protein_bound =
| metabolism =
| elimination_half-life =
| excretion =
| CAS_number_Ref = {{cascite|correct|??}}
| CAS_number = 519-95-9
| ATC_prefix = none
| ATC_suffix =
| ATC_supplemental =
| PubChem = 10617
| DrugBank_Ref = {{drugbankcite|changed|drugbank}}
| DrugBank = DB08975
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = UZ5LMI200P
| ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}}
| ChemSpiderID = 10172
| ChEMBL_Ref = {{ebicite|changed|EBI}}
| ChEMBL = 2106357
| chemical_formula =
| C=20 | H=14 | O=3
| molecular_weight = 302.323 g/mol
| smiles = C1=CC2=C3C(=C1)C4=C(C3=CC=C2)C=C(C=C4)C(=O)CCC(=O)O
| StdInChI_Ref = {{stdinchicite|changed|chemspider}}
| StdInChI = 1S/C20H14O3/c21-18(9-10-19(22)23)13-7-8-14-15-5-1-3-12-4-2-6-16(20(12)15)17(14)11-13/h1-8,11H,9-10H2,(H,22,23)
| StdInChIKey_Ref = {{stdinchicite|changed|chemspider}}
| StdInChIKey = QOBAOSCOLAGPKI-UHFFFAOYSA-N
| melting_point = 195
| solubility = soluble in methanol, ethanol, sodium carbonate
}}Florantyrone (INN; also known as Fluorantyrone) is a drug used in the treatment of biliary dyskinesia. It is also known as a cholagogue and choleretic.[1]

It is manufactured from fluoranthene and succinic anhydride in the presence of aluminum chloride in a nitrobenzene solution. (US PATENT 2,560,425 (1951 To Miles Lab)).

References

1. ^{{cite web|title=florantyrone - Compound Summary|url=https://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?q=all&cid=10617|publisher=PubChem Compound - National Center for Biotechnology Information|accessdate=15 November 2011}}
{{pharma-stub}}

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