| 词条 | Fluvalinate | ||||||||
| 释义 |
| Verifiedfields = changed | verifiedrevid = 431991211 | IUPAC_name = [Cyano-(3-phenoxyphenyl)methyl] 2-[2-chloro-4-(trifluoromethyl)anilino]-3-methylbutanoate | image = Fluvalinat Structural Formula V3.svg | tradename = | Drugs.com = {{drugs.com|international|fluvalinate}} | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = | routes_of_administration = | bioavailability = | protein_bound = | metabolism = | elimination_half-life = | excretion = | CAS_number_Ref = {{cascite|changed|??}} | CAS_number = 69409-94-5 | CAS_supplemental = {{CAS|102851-06-9}} (tau-fluvalinate) | ATCvet = yes | ATC_prefix = P53 | ATC_suffix = AC10 | ATC_supplemental = | PubChem = 50516 | DrugBank_Ref = {{drugbankcite|correct|drugbank}} | DrugBank = | KEGG_Ref = {{keggcite|correct|kegg}} | KEGG = C18790 | ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}} | ChemSpiderID = 45805 | StdInChI_Ref = {{stdinchicite|changed|chemspider}} | StdInChI = 1S/C26H22ClF3N2O3/c1-16(2)24(32-22-12-11-18(14-21(22)27)26(28,29)30)25(33)35-23(15-31)17-7-6-10-20(13-17)34-19-8-4-3-5-9-19/h3-14,16,23-24,32H,1-2H3 | StdInChIKey_Ref = {{stdinchicite|changed|chemspider}} | StdInChIKey = INISTDXBRIBGOC-UHFFFAOYSA-N | chemical_formula = | C=26 | H=22 | Cl=1 | F=3 | N=2 | O=3 | molecular_weight = 502.913 g/mol | smiles = CC(C)C(C(=O)OC(C#N)C1=CC(=CC=C1)OC2=CC=CC=C2)NC3=C(C=C(C=C3)C(F)(F)F)Cl }} Fluvalinate is a synthetic pyrethroid chemical compound contained as an active agent in the products Apistan, Klartan, and Minadox, that is an acaricide (specifically, a miticide), that is commonly used to control varroa mites in honey bee colonies,{{cn|date=August 2016}} infestations that constitute a significant disease of such insects. Fluvalinate is a stable, non-volatile[1], viscous heavy oil (technical) soluble in organic solvents.[2] Its effectiveness was first demonstrated in France and Israel.{{when?|date=August 2016}}{{cn|date=August 2016}} Although the compound may be found in drones, a study has found honey samples virtually absent of fluvalinate, on account of its affinity to beeswax.[3]{{better source|date=August 2016}} StereoisomerismFluvalinate is synthesized from racemic valine [(RS)-valine], the synthesis is not diastereoselective. Thus, fluvinate is a mixture of four stereoisomers, each approx. 25 %.[4]
See also
References1. ^{{citation |url=http://sitem.herts.ac.uk/aeru/ppdb/en/Reports/608.htm |title=tau-fluvalinate |work=Pesticide Properties DataBase |publisher=University of Hertfordshire |accessdate=June 24, 2017}} 2. ^1 {{citation |url=https://pubchem.ncbi.nlm.nih.gov/compound/Tau-fluvalinate |title=Tau-fluvalinate |work=PubChem. The Open Chemistry Database |publisher=National Institutes of Health |accessdate=June 24, 2017}} 3. ^{{cite journal | author = MAF Biosecurity New Zealand | date = 2001 | title = A Review of Treatment Options for Control of Varroa Mite in New Zealand [HortResearch Client Report No. 2001/249] | url = http://www.biosecurity.govt.nz/files/pests/varroa/papers/varroa-treatment-options.pdf | access-date = 28 August 2016 | quote = This report was commissioned by MAF to aid in internal decision making only. This report in no way constitutes MAF's advice to beekeepers and is useful only as background information.}}{{better source|date=August 2016}} 4. ^{{citation|surname1=David M. Whitacre|title=Reviews of environmental contamination and toxicology|publisher=Springer|page=125|isbn=978-1-4614-3280-7|date=2012|language=German|url={{Google books|L3gpxVLsbMYC&pg||page=125}}}} Further reading
External links
6 : Pyrethroids|Chloroarenes|Trifluoromethyl compounds|Nitriles|Phenol ethers|Cyanohydrin esters |
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