| 释义 |
- References
- Further reading
{{Infobox_gene}}Fibroblast growth factor receptor substrate 3 is a protein that in humans is encoded by the FRS3 gene.[1][2][3]The protein encoded by this gene is a substrate for the fibroblast growth factor receptor. It is found in peripheral plasma membrane and functions in linking FGF receptor stimulation to activators of Ras.[4] References1. ^{{cite journal |vauthors=Wang JK, Xu H, Li HC, Goldfarb M | title = Broadly expressed SNT-like proteins link FGF receptor stimulation to activators of Ras | journal = Oncogene | volume = 13 | issue = 4 | pages = 721–9 |date=Oct 1996 | pmid = 8761293 | pmc = | doi = }}
2. ^{{cite journal |vauthors=Xu H, Lee KW, Goldfarb M | title = Novel recognition motif on fibroblast growth factor receptor mediates direct association and activation of SNT adapter proteins | journal = J Biol Chem | volume = 273 | issue = 29 | pages = 17987–90 |date=Aug 1998 | pmid = 9660748 | pmc = | doi =10.1074/jbc.273.29.17987 }}
3. ^{{cite web | title = Entrez Gene: FRS3 fibroblast growth factor receptor substrate 3| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10817| accessdate = }}
4. ^{{cite web | title = Entrez Gene: FRS3 fibroblast growth factor receptor substrate 3| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10817| accessdate = }}
Further reading{{refbegin | 2}}- {{cite journal |vauthors=Lim YP, Low BC, Lim J |title=Association of atypical protein kinase C isotypes with the docker protein FRS2 in fibroblast growth factor signaling. |journal=J. Biol. Chem. |volume=274 |issue= 27 |pages= 19025–34 |year= 1999 |pmid= 10383403 |doi=10.1074/jbc.274.27.19025 |display-authors=etal}}
- {{cite journal |vauthors=Ong SH, Guy GR, Hadari YR |title=FRS2 proteins recruit intracellular signaling pathways by binding to diverse targets on fibroblast growth factor and nerve growth factor receptors. |journal=Mol. Cell. Biol. |volume=20 |issue= 3 |pages= 979–89 |year= 2000 |pmid= 10629055 |doi=10.1128/MCB.20.3.979-989.2000 | pmc=85215 |display-authors=etal}}
- {{cite journal |vauthors=Yamada M, Suzuki K, Mizutani M |title=Analysis of tyrosine phosphorylation-dependent protein-protein interactions in TrkB-mediated intracellular signaling using modified yeast two-hybrid system. |journal=J. Biochem. |volume=130 |issue= 1 |pages= 157–65 |year= 2001 |pmid= 11432792 |doi= 10.1093/oxfordjournals.jbchem.a002955|display-authors=etal}}
- {{cite journal |vauthors=Yan KS, Kuti M, Yan S |title=FRS2 PTB domain conformation regulates interactions with divergent neurotrophic receptors. |journal=J. Biol. Chem. |volume=277 |issue= 19 |pages= 17088–94 |year= 2002 |pmid= 11877385 |doi= 10.1074/jbc.M107963200 |display-authors=etal}}
- {{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |display-authors=etal}}
- {{cite journal |vauthors=Ranzi V, Meakin SO, Miranda C |title=The signaling adapters fibroblast growth factor receptor substrate 2 and 3 are activated by the thyroid TRK oncoproteins. |journal=Endocrinology |volume=144 |issue= 3 |pages= 922–8 |year= 2003 |pmid= 12586769 |doi=10.1210/en.2002-221002 |display-authors=etal}}
- {{cite journal |vauthors=Mungall AJ, Palmer SA, Sims SK |title=The DNA sequence and analysis of human chromosome 6. |journal=Nature |volume=425 |issue= 6960 |pages= 805–11 |year= 2003 |pmid= 14574404 |doi= 10.1038/nature02055 |display-authors=etal}}
- {{cite journal |vauthors=Gotoh N, Laks S, Nakashima M |title=FRS2 family docking proteins with overlapping roles in activation of MAP kinase have distinct spatial-temporal patterns of expression of their transcripts. |journal=FEBS Lett. |volume=564 |issue= 1-2 |pages= 14–8 |year= 2004 |pmid= 15094036 |doi= 10.1016/S0014-5793(04)00287-X |display-authors=etal}}
- {{cite journal |vauthors=Hassel S, Eichner A, Yakymovych M |title=Proteins associated with type II bone morphogenetic protein receptor (BMPR-II) and identified by two-dimensional gel electrophoresis and mass spectrometry. |journal=Proteomics |volume=4 |issue= 5 |pages= 1346–58 |year= 2004 |pmid= 15188402 |doi= 10.1002/pmic.200300770 |display-authors=etal}}
- {{cite journal |vauthors=Huang L, Gotoh N, Zhang S |title=SNT-2 interacts with ERK2 and negatively regulates ERK2 signaling in response to EGF stimulation. |journal=Biochem. Biophys. Res. Commun. |volume=324 |issue= 3 |pages= 1011–7 |year= 2004 |pmid= 15485655 |doi= 10.1016/j.bbrc.2004.09.152 |display-authors=etal}}
- {{cite journal |vauthors=Gerhard DS, Wagner L, Feingold EA |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 |display-authors=etal}}
- {{cite journal |vauthors=Harada A, Katoh H, Negishi M |title=Direct interaction of Rnd1 with FRS2 beta regulates Rnd1-induced down-regulation of RhoA activity and is involved in fibroblast growth factor-induced neurite outgrowth in PC12 cells. |journal=J. Biol. Chem. |volume=280 |issue= 18 |pages= 18418–24 |year= 2005 |pmid= 15738000 |doi= 10.1074/jbc.M411356200 }}
- {{cite journal |vauthors=Huang L, Watanabe M, Chikamori M |title=Unique role of SNT-2/FRS2beta/FRS3 docking/adaptor protein for negative regulation in EGF receptor tyrosine kinase signaling pathways. |journal=Oncogene |volume=25 |issue= 49 |pages= 6457–66 |year= 2006 |pmid= 16702953 |doi= 10.1038/sj.onc.1209656 |display-authors=etal}}
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