“Fucose-1-phosphate guanylyltransferase”的意思、由来-开放百科全书

词条

Fucose-1-phosphate guanylyltransferase

释义

References

{{enzyme
| Name = fucose-1-phosphate guanylyltransferase
| EC_number = 2.7.7.30
| CAS_number = 9033-14-1
| IUBMB_EC_number = 2/7/7/30
| GO_code = 0047341
| image =
| width =
| caption =
}}

In enzymology, a fucose-1-phosphate guanylyltransferase ({{EC number|2.7.7.30}}) is an enzyme that catalyzes the chemical reaction

GTP + beta-L-fucose 1-phosphate diphosphate + GDP-L-fucose

Thus, the two substrates of this enzyme are GTP and beta-L-fucose 1-phosphate, whereas its two products are diphosphate and GDP-L-fucose.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing nucleotide groups (nucleotidyltransferases). The systematic name of this enzyme class is GTP:beta-L-fucose-1-phosphate guanylyltransferase. Other names in common use include GDP fucose pyrophosphorylase, guanosine diphosphate L-fucose pyrophosphorylase, GDP-L-fucose pyrophosphorylase, GDP-fucose pyrophosphorylase, and GTP:L-fucose-1-phosphate guanylyltransferase. This enzyme participates in fructose and mannose metabolism.

References

{{cite journal |vauthors=Ishihara H, Heath EC | date = 1968 | title = The metabolism of L-fucose. IV. The biosynthesis of guanosine diphosphate L-fucose in porcine liver | journal = J. Biol. Chem. | volume = 243 | pages = 1110–5 | pmid = 5646162 | issue = 6 }}

2 : EC 2.7.7|Enzymes of unknown structure

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