“Galactosylgalactosylglucosylceramidase”的意思、由来-开放百科全书

词条

Galactosylgalactosylglucosylceramidase

释义

References

{{enzyme
| Name = galactosylgalactosylglucosylceramidase
| EC_number = 3.2.1.47
| CAS_number = 9023-01-2
| IUBMB_EC_number = 3/2/1/47
| GO_code = 0017041
| image =
| width =
| caption =
}}

In enzymology, a galactosylgalactosylglucosylceramidase ({{EC number|3.2.1.47}}) is an enzyme that catalyzes the chemical reaction

D-galactosyl-D-galactosyl-D-glucosyl-N-acylsphingosine + H₂O D-galactose + lactosyl-N-acylsphingosine

Thus, the two substrates of this enzyme are D-galactosyl-D-galactosyl-D-glucosyl-N-acylsphingosine and H₂O, whereas its two products are D-galactose and lactosyl-N-acylsphingosine.

This enzyme belongs to the family of hydrolases, specifically those glycosidases that hydrolyse O- and S-glycosyl compounds. The systematic name of this enzyme class is D-galactosyl-D-galactosyl-D-glucosyl-N-acylsphingosine galactohydrolase. Other names in common use include trihexosyl ceramide galactosidase, ceramide trihexosidase, ceramidetrihexoside alpha-galactosidase, trihexosylceramide alpha-galactosidase, and ceramidetrihexosidase.

References

{{cite journal |vauthors=Brady RO, Gal AE, Bradley RM, Martensson E | date = 1967 | title = The metabolism of ceramide trihexosides. I. Purification and properties of an enzyme that cleaves the terminal galactose molecule of galactosylgalactosylglucosylceramide | journal = J. Biol. Chem. | volume = 242 | pages = 1021–6 | pmid = 6020428 | issue = 5 }}

2 : EC 3.2.1|Enzymes of unknown structure

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