George Bryan (1731–1791) was a Pennsylvania businessman, statesman and politician of the Revolutionary era.

George Bryan may also refer to:

• George Bryan (actor) (fl. 1586–1613), actor in English Renaissance theatre
• George Seabrook Bryan (1809–1905), U.S. federal judge
• George Bryan (politician, died 1843), Irish Member of Parliament in the British House of Commons
• George Leopold Bryan (1828–1880), Irish Member of Parliament in the British House of Commons
• George D. Bryan (1845–1919), Mayor of Charleston, South Carolina, United States
• George H. Bryan (1864–1928), British mathematician and aerospace engineer
• George Bryan (British businessman) (1921–2013), British founder and owner of Drayton Manor Theme Park
• George W. Bryan (born 1946), American CEO of Sara Lee Foods, Senior Vice President of Sara Lee Corporation, and founder of Old Waverly Golf Club

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