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词条 Gibbus deformity
释义

  1. References

Gibbus deformity is a form of structural kyphosis typically found in the upper lumbar and lower thoracic vertebrae, where one or more adjacent vertebrae become wedged. Gibbus deformity most often develops in young children as a result of spinal tuberculosis and is the result of collapse of vertebral bodies.[1][2][3] This can in turn lead to spinal cord compression causing paraplegia.[4][5]

In addition to tuberculosis, other possible causes of gibbus deformity include pathological diseases, hereditary and congenital conditions, and physical trauma to the spine that results in injury.[6][7] Gibbus deformity may result from the sail vertebrae associated with cretinism (the childhood form of hypothyroidism), mucopolysaccharidosis (MPS), and certain congenital syndromes, including achondroplasia.[8] Because most children with MPS I (Hurler Syndrome) also exhibit symptoms of a gibbus deformity, the latter can possibly be used to identify the former.[9]

Gibbus deformity is included in a subset of structural kyphosis that is distinguished by a higher-degree angle in the spinal curve that is specific to these forms of kyphosis. Other conditions within this subset include Pott’s disease and Scheuermann kyphosis, but gibbus deformity is marked by an especially sharp angle. Viewed from behind, the resulting hunchback is more easily seen when bending forward.[10] A kyphosis of >70° can be an indication of the need for surgery and these surgeries can be necessary for children as young as two years old, with a reported average of 8 years of age.[9]

References

1. ^Kasper D.L. et al., Harrisons principles of internal medicine, 16.ed, 2005 p.958
2. ^{{Cite journal|last=Batirel|first=A.|last2=Erdem|first2=H.|last3=Sengoz|first3=G.|last4=Pehlivanoglu|first4=F.|last5=Ramosaco|first5=E.|last6=Gülsün|first6=S.|last7=Tekin|first7=R.|last8=Mete|first8=B.|last9=Balkan|first9=İ.İ.|title=The course of spinal tuberculosis (Pott disease): results of the multinational, multicentre Backbone-2 study|url=http://linkinghub.elsevier.com/retrieve/pii/S1198743X15007302|journal=Clinical Microbiology and Infection|volume=21|issue=11|pages=1008.e9–1008.e18|doi=10.1016/j.cmi.2015.07.013|pmid=26232534|year=2015}}
3. ^{{Cite journal|last=Garg|first=Ravindra Kumar|last2=Somvanshi|first2=Dilip Singh|date=2011-09-01|title=Spinal tuberculosis: A review|journal=The Journal of Spinal Cord Medicine|volume=34|issue=5|pages=440–454|doi=10.1179/2045772311y.0000000023|issn=1079-0268|pmid=22118251|pmc=3184481}}
4. ^Davidson's Principles and Practice of Medicine, 20th Ed, 2006.
5. ^{{Cite journal|last=Ghandi|first=Mehak|last2=Aycock|first2=Ryan D.|last3=Berwald|first3=Nicole|last4=Hahn|first4=Barry|title=Gibbus Deformity|url=http://linkinghub.elsevier.com/retrieve/pii/S0736467915003418|journal=The Journal of Emergency Medicine|volume=49|issue=3|pages=340–341|doi=10.1016/j.jemermed.2015.04.004|pmid=26095218|year=2015}}
6. ^{{Cite journal|last=Yaman|first=Onur|last2=Dalbayrak|first2=Sedat|title=Kyphosis and review of the literature|journal=Turkish Neurosurgery|language=English|volume=24|issue=4|pages=455–65|doi=10.5137/1019-5149.jtn.8940-13.0|pmid=25050667|issn=1019-5149|year=2013}}
7. ^{{Cite book|title=Abnormal Skeletal Phenotypes|last=Castriota-Scanderbeg|first=Alessandro|date=2005|publisher=Springer, Berlin, Heidelberg|isbn=978-3540303619|pages=167–232|language=en|doi=10.1007/3-540-30361-8_3|chapter = Spine}}
8. ^{{Cite journal|last=Hecht|first=Jacqueline T.|last2=Butler|first2=Ian J.|title=Neurologic Morbidity Associated With Achondroplasia|journal=Journal of Child Neurology|language=en|volume=5|issue=2|pages=84–97|doi=10.1177/088307389000500203|pmid=2161033|year=1990}}
9. ^{{Cite journal|last=White|first=K. K.|date=2011-12-01|title=Orthopaedic aspects of mucopolysaccharidoses|url=https://academic.oup.com/rheumatology/article/50/suppl_5/v26/1778987|journal=Rheumatology|language=en|volume=50|issue=suppl 5|pages=v26–v33|doi=10.1093/rheumatology/ker393|pmid=22210667|issn=1462-0324}}
10. ^{{Cite news|url=http://www.spineuniverse.com/displayarticle.php/article1437.html|title=Kyphosis: Description and Diagnosis|work=SpineUniverse|access-date=2017-11-15|language=en}}
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1 : Skeletal disorders

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