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词条 Glidant
释义

  1. Examples

  2. Mechanism of action

  3. References

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A glidant is a substance that is added to a powder to improve its flowability. A glidant will only work at a certain range of concentrations. Above a certain concentration, the glidant will in fact function to inhibit flowability.

In tablet manufacture, glidants are usually added just prior to compression.

Examples

Examples of glidants include magnesium stearate, fumed silica (colloidal silicon dioxide), starch and talc.[1]

Mechanism of action

A glidant's effect is due to the counter-action of factors that cause poor flowability of powders. For instance, correcting surface irregularity, reducing interparticular friction and decreasing surface charge. The result is a decrease in the angle of repose which is an indication of an enhanced powder's flowability.

References

1. ^{{cite web|title=SMI: Talc as a Glidant & Lubricant|url=http://www.specialtyminerals.com/specialty-applications/specialty-markets-for-minerals/nutritional-supplements/talc-as-a-glidant-lubricant/|publisher=2012 Specialty Minerals Inc.|accessdate=19 March 2014}}
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1 : Granularity of materials

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