1. Structural studies

2. References

In enzymology, a glycerol-3-phosphate cytidylyltransferase ({{EC number|2.7.7.39}}) is an enzyme that catalyzes the chemical reaction

CTP + sn-glycerol 3-phosphate diphosphate + CDP-glycerol

Thus, the two substrates of this enzyme are CTP and sn-glycerol 3-phosphate, whereas its two products are diphosphate and CDP-glycerol.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing nucleotide groups (nucleotidyltransferases). The systematic name of this enzyme class is CTP:sn-glycerol-3-phosphate cytidylyltransferase. Other names in common use include CDP-glycerol pyrophosphorylase, cytidine diphosphoglycerol pyrophosphorylase, cytidine diphosphate glycerol pyrophosphorylase, CTP:glycerol 3-phosphate cytidylyltransferase, and Gro-PCT. This enzyme participates in glycerophospholipid metabolism.

Structural studies

As of late 2007, 3 structures have been solved for this class of enzymes, with PDB accession codes {{PDB link|1COZ}}, {{PDB link|1N1D}}, and {{PDB link|2B7L}}.

References

• {{cite journal | vauthors = Shaw DR | title = Pyrophosphorolysis and enzymic synthesis of cytidine diphosphate glycerol and cytidine diphosphate ribitol | journal = The Biochemical Journal | volume = 82 | pages = 297–312 | date = February 1962 | pmid = 13911452 | pmc = 1243453 }}

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