“Glycine betaine aldehyde”的意思、由来-开放百科全书

词条

Glycine betaine aldehyde

释义

Chemical structure
Biological function
References

{{Chembox
| Reference =
| Name = Glycine betaine aldehyde
| ImageFile = Betaine aldehyde.svg
| ImageSize = 200px
| IUPACName = N,N,N-trimethyl-2-oxoethanaminium
| OtherNames = Betaine aldehyde
|Section1={{Chembox Identifiers
| CASNo = 7418-61-3
| CASNo1 = 7758-31-8
| CASNo1_Comment = (chloride salt)
| ChemSpiderID = 244
| InChI = 1/C5H12NO/c1-6(2,3)4-5-7/h5H,4H2,1-3H3/q+1
| InChIKey = SXKNCCSPZDCRFD-UHFFFAOYAL
| PubChem = 249
| SMILES = O=CC[N+](C)(C)C
| ChEBI = 15710
| KEGG = C00576
}}
|Section2={{Chembox Properties
| C=5 | H=12 | N=1 | O=1
| Appearance =
| Density =
| MeltingPt =
| BoilingPt =
| Solubility = }}
|Section3={{Chembox Hazards
| MainHazards =
| FlashPt =
| AutoignitionPt =
}}
}}Glycine betaine aldehyde, often simply called betaine aldehyde,^[1] is an intermediate in the metabolism of glycine, serine and threonine. The human aldehyde dehydrogenase ({{EC number|1.2.1.3}}) stimulates the transformation of betaine aldehyde to glycine betaine. Betaine aldehyde is a substrate for choline dehydrogenase (mitochondrial).^[2]

Chemical structure

Glycine betaine aldehyde is a short chain aldehyde and quaternary ammonium compound. It can be considered a derivative of the amino acid glycine. Its chemical formula is C₅H₁₂NO⁺.

Biological function

Glycine betaine aldehyde is a component of glycine, serine and threonine metabolism. It also serves as an osmolyte.

It can be found in cytoplasm and mitochondria within the kidney, neurons, and stratum corneum.^[3]

References

1. ^Betaine aldehyde, Biological Magnetic Resonance Data Bank
2. ^{{cite journal |author=Yilmaz JL, Bülow L. |title= Enhanced stress tolerance in Escherichia coli and Nicotiana tabacum expressing a betaine aldehyde dehydrogenase/choline dehydrogenase fusion protein.|journal=Biotechnol Prog. |volume=18|issue=6 |pages=1176–82|date=December 2002 |pmid=12467448|url= |doi=10.1021/bp020057k}}
3. ^Metabocard for Dimethylglycine, Human Metabolome Database

2 : Aldehydes|Quaternary ammonium compounds

随便看

开放百科全书收录14589846条英语、德语、日语等多语种百科知识，基本涵盖了大多数领域的百科知识，是一部内容自由、开放的电子版国际百科全书。