| 释义 |
- See also
- References
- Further reading
{{Infobox_gene}}Glypican-5 is a protein that in humans is encoded by the GPC5 gene.[1][2]Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation.[3] See alsoReferences1. ^{{cite journal |vauthors=Veugelers M, Vermeesch J, Reekmans G, Steinfeld R, Marynen P, David G | title = Characterization of glypican-5 and chromosomal localization of human GPC5, a new member of the glypican gene family | journal = Genomics | volume = 40 | issue = 1 | pages = 24–30 |date=Jun 1997 | pmid = 9070915 | pmc = | doi = 10.1006/geno.1996.4518 }}
2. ^{{cite web | title = Entrez Gene: GPC5 glypican 5| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2262| accessdate = }}
3. ^{{cite web | title = Entrez Gene: GPC5 glypican 5| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2262| accessdate = }}
Further reading{{refbegin | 2}}- {{cite journal |vauthors=De Cat B, David G |title=Developmental roles of the glypicans. |journal=Semin. Cell Dev. Biol. |volume=12 |issue= 2 |pages= 117–25 |year= 2001 |pmid= 11292377 |doi= 10.1006/scdb.2000.0240 }}
- {{cite journal |vauthors=Watanabe K, Yamada H, Yamaguchi Y |title=K-glypican: a novel GPI-anchored heparan sulfate proteoglycan that is highly expressed in developing brain and kidney. |journal=J. Cell Biol. |volume=130 |issue= 5 |pages= 1207–18 |year= 1995 |pmid= 7657705 |doi=10.1083/jcb.130.5.1207 | pmc=2120559 }}
- {{cite journal |vauthors=Saunders S, Paine-Saunders S, Lander AD |title=Expression of the cell surface proteoglycan glypican-5 is developmentally regulated in kidney, limb, and brain. |journal=Dev. Biol. |volume=190 |issue= 1 |pages= 78–93 |year= 1997 |pmid= 9331333 |doi= 10.1006/dbio.1997.8690 }}
- {{cite journal |vauthors=Veugelers M, De Cat B, Delande N, etal |title=A 4-Mb BAC/PAC contig and complete genomic structure of the GPC5/GPC6 gene cluster on chromosome 13q32. |journal=Matrix Biol. |volume=20 |issue= 5–6 |pages= 375–85 |year= 2002 |pmid= 11566272 |doi=10.1016/S0945-053X(01)00143-3 }}
- {{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 }}
- {{cite journal |vauthors=Yu W, Inoue J, Imoto I, etal |title=GPC5 is a possible target for the 13q31-q32 amplification detected in lymphoma cell lines |journal=J. Hum. Genet. |volume=48 |issue= 6 |pages= 331–5 |year= 2004 |pmid= 12721791 |doi= 10.1007/s10038-003-0026-2 }}
- {{cite journal |vauthors=Dunham A, Matthews LH, Burton J, etal |title=The DNA sequence and analysis of human chromosome 13 |journal=Nature |volume=428 |issue= 6982 |pages= 522–8 |year= 2004 |pmid= 15057823 |doi= 10.1038/nature02379 | pmc=2665288 }}
- {{cite journal |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
{{refend}}{{gene-13-stub}} |