| 释义 |
- See also
- References
- Further reading
- External links
{{Infobox_gene}}Glypican-6 is a protein that in humans is encoded by the GPC6 gene.[1][2]The glypicans comprise a family of glycosylphosphatidylinositol-anchored heparan sulfate proteoglycans. The glypicans have been implicated in the control of cell growth and division. Glypican 6 is a putative cell surface coreceptor for growth factors, extracellular matrix proteins, proteases and anti-proteases.[2] See alsoReferences1. ^{{cite journal |vauthors=Paine-Saunders S, Viviano BL, Saunders S | title = GPC6, a novel member of the glypican gene family, encodes a product structurally related to GPC4 and is colocalized with GPC5 on human chromosome 13 | journal = Genomics | volume = 57 | issue = 3 | pages = 455–8 |date=Aug 1999 | pmid = 10329016 | pmc = | doi = 10.1006/geno.1999.5793 }}
2. ^1 {{cite web | title = Entrez Gene: GPC6 glypican 6| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10082| accessdate = }}
Further reading{{refbegin | 2}}- {{cite journal |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
- {{cite journal |vauthors=Dunham A, Matthews LH, Burton J, etal |title=The DNA sequence and analysis of human chromosome 13 |journal=Nature |volume=428 |issue= 6982 |pages= 522–8 |year= 2004 |pmid= 15057823 |doi= 10.1038/nature02379 | pmc=2665288 }}
- {{cite journal |vauthors=Clark HF, Gurney AL, Abaya E, etal |title=The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment |journal=Genome Res. |volume=13 |issue= 10 |pages= 2265–70 |year= 2003 |pmid= 12975309 |doi= 10.1101/gr.1293003 | pmc=403697 }}
- {{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 }}
- {{cite journal |vauthors=Veugelers M, De Cat B, Ceulemans H, etal |title=Glypican-6, a new member of the glypican family of cell surface heparan sulfate proteoglycans |journal=J. Biol. Chem. |volume=274 |issue= 38 |pages= 26968–77 |year= 1999 |pmid= 10480909 |doi=10.1074/jbc.274.38.26968 }}
- {{cite journal |vauthors=Watanabe K, Yamada H, Yamaguchi Y |title=K-glypican: a novel GPI-anchored heparan sulfate proteoglycan that is highly expressed in developing brain and kidney |journal=J. Cell Biol. |volume=130 |issue= 5 |pages= 1207–18 |year= 1995 |pmid= 7657705 |doi=10.1083/jcb.130.5.1207 | pmc=2120559 }}
{{refend}}External links- {{UCSC genome browser|GPC6}}
- {{UCSC gene details|GPC6}}
{{gene-13-stub}} |