释义 |
- References
- Further reading
{{Infobox_gene}}Guanine nucleotide-binding protein G(t) subunit alpha-3, also known as gustducin alpha-3 chain, is a protein that in humans is encoded by the GNAT3 gene.[1]Gustducin alpha-3 chain is a subunit of the heterotrimeric protein gustducin that is responsible for basic taste. References1. ^{{cite web | title = Entrez Gene: guanine nucleotide binding protein| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=346562| accessdate = }}
Further reading{{refbegin | 2}}- {{cite journal |vauthors=Oldham WM, Van Eps N, Preininger AM |title=Mechanism of the receptor-catalyzed activation of heterotrimeric G proteins. |journal=Nat. Struct. Mol. Biol. |volume=13 |issue= 9 |pages= 772–7 |year= 2006 |pmid= 16892066 |doi= 10.1038/nsmb1129 |display-authors=etal}}
- {{cite journal |vauthors=Scherer SW, Cheung J, MacDonald JR |title=Human chromosome 7: DNA sequence and biology. |journal=Science |volume=300 |issue= 5620 |pages= 767–72 |year= 2003 |pmid= 12690205 |doi= 10.1126/science.1083423 |pmc=2882961|bibcode = 2003Sci...300..767S |display-authors=etal}}
- {{cite journal |vauthors=Rozengurt N, Wu SV, Chen MC |title=Colocalization of the alpha-subunit of gustducin with PYY and GLP-1 in L cells of human colon. |journal=Am. J. Physiol. Gastrointest. Liver Physiol. |volume=291 |issue= 5 |pages= G792-802 |year= 2006 |pmid= 16728727 |doi= 10.1152/ajpgi.00074.2006 |display-authors=etal}}
- {{cite journal |vauthors=Huang L, Shanker YG, Dubauskaite J |title=Ggamma13 colocalizes with gustducin in taste receptor cells and mediates IP3 responses to bitter denatonium. |journal=Nat. Neurosci. |volume=2 |issue= 12 |pages= 1055–62 |year= 1999 |pmid= 10570481 |doi= 10.1038/15981 |display-authors=etal}}
- {{cite journal |vauthors=Hillier LW, Fulton RS, Fulton LA |title=The DNA sequence of human chromosome 7. |journal=Nature |volume=424 |issue= 6945 |pages= 157–64 |year= 2003 |pmid= 12853948 |doi= 10.1038/nature01782 |bibcode = 2003Natur.424..157H |display-authors=etal}}
- {{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2002 |pmid= 12477932 |doi= 10.1073/pnas.242603899 |pmc=139241|bibcode = 2002PNAS...9916899M |display-authors=etal}}
- {{cite journal |author=Luttrell LM |title=Reviews in molecular biology and biotechnology: transmembrane signaling by G protein-coupled receptors. |journal=Mol. Biotechnol. |volume=39 |issue= 3 |pages= 239–64 |year= 2008 |pmid= 18240029 |doi= 10.1007/s12033-008-9031-1 }}
- {{cite journal |vauthors=Margolskee RF, Dyer J, Kokrashvili Z |title=T1R3 and gustducin in gut sense sugars to regulate expression of Na+-glucose cotransporter 1. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=104 |issue= 38 |pages= 15075–80 |year= 2007 |pmid= 17724332 |doi= 10.1073/pnas.0706678104 |bibcode = 2007PNAS..10415075M |pmc=1986615|display-authors=etal}}
- {{cite journal |vauthors=Takami S, Getchell TV, McLaughlin SK |title=Human taste cells express the G protein alpha-gustducin and neuron-specific enolase. |journal=Brain Res. Mol. Brain Res. |volume=22 |issue= 1-4 |pages= 193–203 |year= 1994 |pmid= 8015379 |doi= 10.1016/0169-328X(94)90047-7 |display-authors=etal}}
- {{cite journal |vauthors=Jang HJ, Kokrashvili Z, Theodorakis MJ |title=Gut-expressed gustducin and taste receptors regulate secretion of glucagon-like peptide-1. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=104 |issue= 38 |pages= 15069–74 |year= 2007 |pmid= 17724330 |doi= 10.1073/pnas.0706890104 |bibcode=2007PNAS..10415069J |pmc=1986614|display-authors=etal}}
- {{cite journal |vauthors=Li X, Staszewski L, Xu H |title=Human receptors for sweet and umami taste. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 7 |pages= 4692–6 |year= 2002 |pmid= 11917125 |doi= 10.1073/pnas.072090199 |pmc=123709|bibcode = 2002PNAS...99.4692L |display-authors=etal}}
- {{cite journal |vauthors=Fehr J, Meyer D, Widmayer P |title=Expression of the G-protein alpha-subunit gustducin in mammalian spermatozoa. |journal=J. Comp. Physiol. A |volume=193 |issue= 1 |pages= 21–34 |year= 2007 |pmid= 17021831 |doi= 10.1007/s00359-006-0168-8 |display-authors=etal}}
- {{cite journal |vauthors=Lambright DG, Noel JP, Hamm HE, Sigler PB |title=Structural determinants for activation of the alpha-subunit of a heterotrimeric G protein. |journal=Nature |volume=369 |issue= 6482 |pages= 621–8 |year= 1994 |pmid= 8208289 |doi= 10.1038/369621a0 |bibcode = 1994Natur.369..621L }}
{{refend}}{{Intracellular signaling peptides and proteins}}{{gene-7-stub}} |