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词条 GNG11
释义

  1. References

  2. Further reading

{{Infobox_gene}}Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 is a protein that in humans is encoded by the GNG11 gene.[1][2]

This gene is a member of the guanine nucleotide-binding protein (G protein) gamma family and encodes a lipid-anchored, cell membrane protein. As a member of the heterotrimeric G protein complex, this protein plays a role in this transmembrane signaling system. This protein is also subject to carboxyl-terminal processing. Decreased expression of this gene is associated with splenic marginal zone lymphomas.[2]

References

1. ^{{cite journal |vauthors=Ray K, Kunsch C, Bonner LM, Robishaw JD | title = Isolation of cDNA clones encoding eight different human G protein gamma subunits, including three novel forms designated the gamma 4, gamma 10, and gamma 11 subunits | journal = J Biol Chem | volume = 270 | issue = 37 | pages = 21765–71 |date=Oct 1995 | pmid = 7665596 | pmc = | doi =10.1074/jbc.270.37.21765 }}
2. ^{{cite web | title = Entrez Gene: GNG11 guanine nucleotide binding protein (G protein), gamma 11| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2791| accessdate = }}

Further reading

{{refbegin | 2}}
  • {{cite journal |vauthors=Downes GB, Gautam N |title=The G protein subunit gene families. |journal=Genomics |volume=62 |issue= 3 |pages= 544–52 |year= 2000 |pmid= 10644457 |doi= 10.1006/geno.1999.5992 }}
  • {{cite journal |title=Toward a complete human genome sequence. |journal=Genome Res. |volume=8 |issue= 11 |pages= 1097–108 |year= 1999 |pmid= 9847074 |doi= 10.1101/gr.8.11.1097}}
  • {{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |display-authors=etal}}
  • {{cite journal |vauthors=Cuello F, Schulze RA, Heemeyer F |title=Activation of heterotrimeric G proteins by a high energy phosphate transfer via nucleoside diphosphate kinase (NDPK) B and Gbeta subunits. Complex formation of NDPK B with Gbeta gamma dimers and phosphorylation of His-266 IN Gbeta. |journal=J. Biol. Chem. |volume=278 |issue= 9 |pages= 7220–6 |year= 2003 |pmid= 12486123 |doi= 10.1074/jbc.M210304200 |display-authors=etal}}
  • {{cite journal |vauthors=Scherer SW, Cheung J, MacDonald JR |title=Human chromosome 7: DNA sequence and biology. |journal=Science |volume=300 |issue= 5620 |pages= 767–72 |year= 2003 |pmid= 12690205 | pmc=2882961 |doi= 10.1126/science.1083423 |display-authors=etal}}
  • {{cite journal |vauthors=Hillier LW, Fulton RS, Fulton LA |title=The DNA sequence of human chromosome 7. |journal=Nature |volume=424 |issue= 6945 |pages= 157–64 |year= 2003 |pmid= 12853948 |doi= 10.1038/nature01782 |display-authors=etal}}
  • {{cite journal |vauthors=Gerhard DS, Wagner L, Feingold EA |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 |display-authors=etal}}
  • {{cite journal |vauthors=Barrios-Rodiles M, Brown KR, Ozdamar B |title=High-throughput mapping of a dynamic signaling network in mammalian cells. |journal=Science |volume=307 |issue= 5715 |pages= 1621–5 |year= 2005 |pmid= 15761153 |doi= 10.1126/science.1105776 |display-authors=etal}}
  • {{cite journal |vauthors=Ruiz-Ballesteros E, Mollejo M, Rodriguez A |title=Splenic marginal zone lymphoma: proposal of new diagnostic and prognostic markers identified after tissue and cDNA microarray analysis. |journal=Blood |volume=106 |issue= 5 |pages= 1831–8 |year= 2005 |pmid= 15914563 |doi= 10.1182/blood-2004-10-3898 |display-authors=etal}}
  • {{cite journal |vauthors=Rual JF, Venkatesan K, Hao T |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 |display-authors=etal}}
  • {{cite journal |vauthors=Hossain MN, Sakemura R, Fujii M, Ayusawa D |title=G-protein gamma subunit GNG11 strongly regulates cellular senescence. |journal=Biochem. Biophys. Res. Commun. |volume=351 |issue= 3 |pages= 645–50 |year= 2007 |pmid= 17092487 |doi= 10.1016/j.bbrc.2006.10.112 }}
{{refend}}{{Intracellular signaling peptides and proteins}}{{gene-7-stub}}
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