“GPLD1”的意思、由来-开放百科全书

Many proteins are tethered to the extracellular face of eukaryotic plasma membranes by a glycosylphosphatidylinositol (GPI) anchor. The GPI-anchor is a glycolipid found on many blood cells. The protein encoded by this gene is a GPI degrading enzyme. Glycosylphosphatidylinositol specific phospholipase D1 hydrolyzes the inositol phosphate linkage in proteins anchored by phosphatidylinositol glycans, thereby releasing the attached protein from the plasma membrane.^[2]

References

1. ^{{cite journal |vauthors=Schofield JN, Rademacher TW | title = Structure and expression of the human glycosylphosphatidylinositol phospholipase D1 (GPLD1) gene | journal = Biochim Biophys Acta | volume = 1494 | issue = 1–2 | pages = 189–94 |date=Dec 2000 | pmid = 11072085 | pmc = | doi = 10.1016/s0167-4781(00)00194-9}}
2. ^¹{{cite web | title = Entrez Gene: GPLD1 glycosylphosphatidylinositol specific phospholipase D1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2822| accessdate = }}
3. ^¹{{cite journal |last=Deeg |first=M A |authorlink= |author2=Bierman E L |author3=Cheung M C |date=Mar 2001 |title=GPI-specific phospholipase D associates with an apoA-I- and apoA-IV-containing complex |journal=J. Lipid Res. |volume=42 |issue=3 |pages=442–51 |publisher= |location = United States| issn = 0022-2275| pmid = 11254757 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = }}

Further reading

{{cite journal |vauthors=Hoener MC, Brodbeck U |title=Phosphatidylinositol-glycan-specific phospholipase D is an amphiphilic glycoprotein that in serum is associated with high-density lipoproteins |journal=Eur. J. Biochem. |volume=206 |issue= 3 |pages= 747–57 |year= 1992 |pmid= 1606959 |doi=10.1111/j.1432-1033.1992.tb16981.x }}

{{cite journal | author=Scallon BJ |title=Primary structure and functional activity of a phosphatidylinositol-glycan-specific phospholipase D |journal=Science |volume=252 |issue= 5004 |pages= 446–8 |year= 1991 |pmid= 2017684 |doi=10.1126/science.2017684 |name-list-format=vanc| author2=Fung WJ | author3=Tsang TC | display-authors=3 | last4=Li | first4=S | last5=Kado-Fong | first5=H | last6=Huang | first6=K. | last7=Kochan | first7=J. |bibcode=1991Sci...252..446S}}

{{cite journal | author=Metz CN |title=Release of GPI-anchored membrane proteins by a cell-associated GPI-specific phospholipase D |journal=EMBO J. |volume=13 |issue= 7 |pages= 1741–51 |year= 1994 |pmid= 7512501 |doi= | pmc=395007 |name-list-format=vanc| author2=Brunner G | author3=Choi-Muira NH | display-authors=3 | last4=Nguyen | first4=H | last5=Gabrilove | first5=J | last6=Caras | first6=IW | last7=Altszuler | first7=N | last8=Rifkin | first8=DB | last9=Wilson | first9=EL }}

{{cite journal |vauthors=Jinnai H, Nakamura S |title=Characterization of phospholipase D activation by GM2 activator in a cell-free system |journal=Kobe Journal of Medical Sciences |volume=45 |issue= 3–4 |pages= 181–90 |year= 2000 |pmid= 10752311 |doi= }}

{{cite journal |vauthors=Deeg MA, Bierman EL, Cheung MC |title=GPI-specific phospholipase D associates with an apoA-I- and apoA-IV-containing complex |journal=J. Lipid Res. |volume=42 |issue= 3 |pages= 442–51 |year= 2001 |pmid= 11254757 |doi= }}

{{cite journal |vauthors=Tang J, Li W |title=[Methodological study on the assay of glycosylphosphatidylinositol-specific phospholipase D activity in serum] |journal=Hunan Yi Ke Da Xue Xue Bao |volume=24 |issue= 2 |pages= 119–22 |year= 2002 |pmid= 11938765 |doi= }}

{{cite journal |vauthors=Slomiany A, Nishikawa H, Slomiany BL |title=Screening and modulation of extracellular signals by mucous barrier. Serum glycosylphosphatidylinositol phospholipase D (GPI-PLD) releases protective mucous barrier from oral mucosa |journal=J. Physiol. Pharmacol. |volume=53 |issue= 1 |pages= 21–38 |year= 2002 |pmid= 11939716 |doi= }}

{{cite journal | author=Jaworek J |title=Sensory nerves in central and peripheral control of pancreatic integrity by leptin and melatonin |journal=J. Physiol. Pharmacol. |volume=53 |issue= 1 |pages= 51–74 |year= 2002 |pmid= 11939719 |doi= |name-list-format=vanc| author2=Bonio J | author3=Leja-Szpa A | display-authors=3 | last4=Nawrot | first4=K | last5=Tomaszewska | first5=MR | last6=Stachura | first6=J | last7=Pawlik | first7=WW | last8=Konturek | first8=SJ }}

{{cite journal |vauthors=Deeg MA, Bowen RF |title=Phosphorylation decreases trypsin activation and apolipoprotein al binding to glycosylphosphatidylinositol-specific phospholipase D |journal=Biochem. Cell Biol. |volume=80 |issue= 2 |pages= 253–60 |year= 2002 |pmid= 11989719 |doi=10.1139/o02-004 }}

{{cite journal |vauthors=Xiaotong H, Hannocks MJ, Hampson I, Brunner G |title=GPI-specific phospholipase D mRNA expression in tumor cells of different malignancy |journal=Clin. Exp. Metastasis |volume=19 |issue= 4 |pages= 291–9 |year= 2002 |pmid= 12090469 |doi=10.1023/A:1015545407700 }}

{{cite journal |vauthors=Magnusson P, Sharp CA, Farley JR |title=Different distributions of human bone alkaline phosphatase isoforms in serum and bone tissue extracts |journal=Clin. Chim. Acta |volume=325 |issue= 1–2 |pages= 59–70 |year= 2003 |pmid= 12367767 |doi=10.1016/S0009-8981(02)00248-6 }}

{{cite journal | author=Strausberg RL |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |name-list-format=vanc| author2=Feingold EA | author3=Grouse LH | display-authors=3 | last4=Derge | first4=JG | last5=Klausner | first5=RD | last6=Collins | first6=FS | last7=Wagner | first7=L | last8=Shenmen | first8=CM | last9=Schuler | first9=GD |bibcode=2002PNAS...9916899M}}

{{cite journal |vauthors=Tang JH, Gu SL, Zhang XJ |title=[Preliminary study of the gene structure of human glycosylphosphatidylinositol specific phospholipase D] |journal=Hunan Yi Ke Da Xue Xue Bao |volume=26 |issue= 2 |pages= 95–7 |year= 2003 |pmid= 12536633 |doi= }}

{{cite journal | author=Mungall AJ |title=The DNA sequence and analysis of human chromosome 6 |journal=Nature |volume=425 |issue= 6960 |pages= 805–11 |year= 2003 |pmid= 14574404 |doi= 10.1038/nature02055 |name-list-format=vanc| author2=Palmer SA | author3=Sims SK | display-authors=3 | last4=Edwards | first4=C. A. | last5=Ashurst | first5=J. L. | last6=Wilming | first6=L. | last7=Jones | first7=M. C. | last8=Horton | first8=R. | last9=Hunt | first9=S. E. }}

{{cite journal |vauthors=Kurtz TA, Fineberg NS, Considine RV, Deeg MA |title=Insulin resistance is associated with increased serum levels of glycosylphosphatidylinositol-specific phospholipase D |journal=Metab. Clin. Exp. |volume=53 |issue= 2 |pages= 138–9 |year= 2004 |pmid= 14767861 |doi=10.1016/j.metabol.2003.09.004 }}

{{cite journal | author=Gerhard DS |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 |name-list-format=vanc| author2=Wagner L | author3=Feingold EA | display-authors=3 | last4=Shenmen | first4=CM | last5=Grouse | first5=LH | last6=Schuler | first6=G | last7=Klein | first7=SL | last8=Old | first8=S | last9=Rasooly | first9=R }}

{{cite journal | author=Lugli EB |title=Characterization of primate trypanosome lytic factors |journal=Mol. Biochem. Parasitol. |volume=138 |issue= 1 |pages= 9–20 |year= 2005 |pmid= 15500911 |doi= 10.1016/j.molbiopara.2004.07.004 |name-list-format=vanc| author2=Pouliot M | author3=Portela Mdel P | display-authors=3 | last4=Loomis | first4=Michael R | last5=Raper | first5=Jayne }}

{{cite journal |vauthors=Everett PB, Senogles SE |title=D3 dopamine receptor activates phospholipase D through a pertussis toxin-insensitive pathway |journal=Neurosci. Lett. |volume=371 |issue= 1 |pages= 34–9 |year= 2005 |pmid= 15500962 |doi= 10.1016/j.neulet.2004.08.033 }}

{{cite journal | author=Mead KI |title=Exocytosis of CTLA-4 is dependent on phospholipase D and ADP ribosylation factor-1 and stimulated during activation of regulatory T cells |journal=J. Immunol. |volume=174 |issue= 8 |pages= 4803–11 |year= 2005 |pmid= 15814706 |doi= 10.4049/jimmunol.174.8.4803|name-list-format=vanc| author2=Zheng Y | author3=Manzotti CN | display-authors=3 | last4=Perry | first4=LC | last5=Liu | first5=MK | last6=Burke | first6=F | last7=Powner | first7=DJ | last8=Wakelam | first8=MJ | last9=Sansom | first9=DM }}

Interactions

References

Further reading