| 释义 |
- References
- Further reading
- See also
{{Infobox_gene}}G protein-coupled receptor 177 (GPR177), commonly known as Wntless, is a human gene[1] that encodes a receptor for Wnt proteins in Wnt-secreting cells.[2]Wntless was shown to be a cargo for the retromer complex.[2] It has been found essential for hair follicle induction.[3] References 1. ^{{cite web | title = Entrez Gene: GPR177 G protein-coupled receptor 177| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=79971| accessdate = }}
2. ^1 {{cite journal | vauthors = Eaton S | title = Retromer retrieves wntless | journal = Developmental Cell | volume = 14 | issue = 1 | pages = 4–6 | date = January 2008 | pmid = 18194646 | doi = 10.1016/j.devcel.2007.12.014 }}
3. ^{{cite journal | vauthors = Fu J, Hsu W | title = Epidermal Wnt controls hair follicle induction by orchestrating dynamic signaling crosstalk between the epidermis and dermis | journal = The Journal of Investigative Dermatology | volume = 133 | issue = 4 | pages = 890–8 | date = April 2013 | pmid = 23190887 | pmc = 3594635| doi = 10.1038/jid.2012.407 }}
Further reading {{refbegin | 2}}- {{cite journal | vauthors = Bänziger C, Soldini D, Schütt C, Zipperlen P, Hausmann G, Basler K | title = Wntless, a conserved membrane protein dedicated to the secretion of Wnt proteins from signaling cells | journal = Cell | volume = 125 | issue = 3 | pages = 509–22 | date = May 2006 | pmid = 16678095 | doi = 10.1016/j.cell.2006.02.049 }}
- {{cite journal | vauthors = Otsuki T, Ota T, Nishikawa T, Hayashi K, Suzuki Y, Yamamoto J, Wakamatsu A, Kimura K, Sakamoto K, Hatano N, Kawai Y, Ishii S, Saito K, Kojima S, Sugiyama T, Ono T, Okano K, Yoshikawa Y, Aotsuka S, Sasaki N, Hattori A, Okumura K, Nagai K, Sugano S, Isogai T | title = Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries | journal = DNA Research | volume = 12 | issue = 2 | pages = 117–26 | year = 2007 | pmid = 16303743 | doi = 10.1093/dnares/12.2.117 }}
- {{cite journal | vauthors = Clark HF, Gurney AL, Abaya E, Baker K, Baldwin D, Brush J, Chen J, Chow B, Chui C, Crowley C, Currell B, Deuel B, Dowd P, Eaton D, Foster J, Grimaldi C, Gu Q, Hass PE, Heldens S, Huang A, Kim HS, Klimowski L, Jin Y, Johnson S, Lee J, Lewis L, Liao D, Mark M, Robbie E, Sanchez C, Schoenfeld J, Seshagiri S, Simmons L, Singh J, Smith V, Stinson J, Vagts A, Vandlen R, Watanabe C, Wieand D, Woods K, Xie MH, Yansura D, Yi S, Yu G, Yuan J, Zhang M, Zhang Z, Goddard A, Wood WI, Godowski P, Gray A | title = The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment | journal = Genome Research | volume = 13 | issue = 10 | pages = 2265–70 | date = October 2003 | pmid = 12975309 | pmc = 403697 | doi = 10.1101/gr.1293003 }}
- {{cite journal | vauthors = Matsuda A, Suzuki Y, Honda G, Muramatsu S, Matsuzaki O, Nagano Y, Doi T, Shimotohno K, Harada T, Nishida E, Hayashi H, Sugano S | title = Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways | journal = Oncogene | volume = 22 | issue = 21 | pages = 3307–18 | date = May 2003 | pmid = 12761501 | doi = 10.1038/sj.onc.1206406 }}
{{refend}} See also - {{MeshName|GPR177+receptor,+human}}
{{transmembranereceptor-stub}}{{NLM content}}{{G protein-coupled receptors}} 1 : G protein-coupled receptors |