| 释义 |
- Interactions
- References
- Further reading
{{Infobox_gene}}Probable G-protein coupled receptor 37 is a protein that in humans is encoded by the GPR37 gene.[1][2] Interactions GPR37 has been shown to interact with HSPA1A[3] and Parkin (ligase).[3][4] GPR37 is a receptor for prosaposin. It was previously thought to be a receptor for head activator, a neuropeptide found in the hydra, but early reports of head activator in mammals were never confirmed.[5] References 1. ^{{cite journal | vauthors = Marazziti D, Golini E, Gallo A, Lombardi MS, Matteoni R, Tocchini-Valentini GP | title = Cloning of GPR37, a gene located on chromosome 7 encoding a putative G-protein-coupled peptide receptor, from a human frontal brain EST library | journal = Genomics | volume = 45 | issue = 1 | pages = 68–77 | date = November 1997 | pmid = 9339362 | pmc = | doi = 10.1006/geno.1997.4900 }}
2. ^{{cite web | title = Entrez Gene: GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like)| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2861| accessdate = }}
3. ^1 {{cite journal | vauthors = Imai Y, Soda M, Hatakeyama S, Akagi T, Hashikawa T, Nakayama KI, Takahashi R | title = CHIP is associated with Parkin, a gene responsible for familial Parkinson's disease, and enhances its ubiquitin ligase activity | journal = Mol. Cell | volume = 10 | issue = 1 | pages = 55–67 | date = July 2002 | pmid = 12150907 | doi = 10.1016/S1097-2765(02)00583-X }}
4. ^{{cite journal | vauthors = Imai Y, Soda M, Inoue H, Hattori N, Mizuno Y, Takahashi R | title = An unfolded putative transmembrane polypeptide, which can lead to endoplasmic reticulum stress, is a substrate of Parkin | journal = Cell | volume = 105 | issue = 7 | pages = 891–902 | date = June 2001 | pmid = 11439185 | doi = 10.1016/S0092-8674(01)00407-X }}
5. ^{{cite journal |first1=Rebecca C.|last1=Meyer |first2=Michelle M.|last2=Giddens |first3=Stacy A.|last3=Schaefer |first4=Randy A.|last4=Hall |title=GPR37 and GPR37L1 are receptors for the neuroprotective and glioprotective factors prosaptide and prosaposin |date=4 June 2013 |journal=Proceedings of the National Academy of Sciences |volume=110 |issue=23 |pages=9529–34 |doi=10.1073/pnas.1219004110 |url=http://www.pnas.org/content/110/23/9529.long |pmid=23690594 |pmc=3677493}}
Further reading {{refbegin | 2}}- {{cite journal | vauthors = Zeng Z, Su K, Kyaw H, Li Y | title = A novel endothelin receptor type-B-like gene enriched in the brain | journal = Biochem. Biophys. Res. Commun. | volume = 233 | issue = 2 | pages = 559–67 | year = 1997 | pmid = 9144577 | doi = 10.1006/bbrc.1997.6408 }}
- {{cite journal | vauthors = Donohue PJ, Shapira H, Mantey SA, Hampton LL, Jensen RT, Battey JF | title = A human gene encodes a putative G protein-coupled receptor highly expressed in the central nervous system | journal = Brain Res. Mol. Brain Res. | volume = 54 | issue = 1 | pages = 152–60 | year = 1998 | pmid = 9526070 | doi = 10.1016/S0169-328X(97)00336-7 }}
- {{cite journal | vauthors = Imai Y, Soda M, Inoue H, Hattori N, Mizuno Y, Takahashi R | title = An unfolded putative transmembrane polypeptide, which can lead to endoplasmic reticulum stress, is a substrate of Parkin | journal = Cell | volume = 105 | issue = 7 | pages = 891–902 | year = 2001 | pmid = 11439185 | doi = 10.1016/S0092-8674(01)00407-X }}
- {{cite journal | vauthors = Imai Y, Soda M, Hatakeyama S, Akagi T, Hashikawa T, Nakayama KI, Takahashi R | title = CHIP is associated with Parkin, a gene responsible for familial Parkinson's disease, and enhances its ubiquitin ligase activity | journal = Mol. Cell | volume = 10 | issue = 1 | pages = 55–67 | year = 2002 | pmid = 12150907 | doi = 10.1016/S1097-2765(02)00583-X }}
- {{cite journal | vauthors = Yang Y, Nishimura I, Imai Y, Takahashi R, Lu B | title = Parkin suppresses dopaminergic neuron-selective neurotoxicity induced by Pael-R in Drosophila | journal = Neuron | volume = 37 | issue = 6 | pages = 911–24 | year = 2003 | pmid = 12670421 | doi = 10.1016/S0896-6273(03)00143-0 }}
- {{cite journal | vauthors = Imai Y, Soda M, Murakami T, Shoji M, Abe K, Takahashi R | title = A product of the human gene adjacent to parkin is a component of Lewy bodies and suppresses Pael receptor-induced cell death | journal = J. Biol. Chem. | volume = 278 | issue = 51 | pages = 51901–10 | year = 2003 | pmid = 14532270 | doi = 10.1074/jbc.M309655200 }}
- {{cite journal | vauthors = Kubota K, Niinuma Y, Kaneko M, Okuma Y, Sugai M, Omura T, Uesugi M, Uehara T, Hosoi T, Nomura Y | title = Suppressive effects of 4-phenylbutyrate on the aggregation of Pael receptors and endoplasmic reticulum stress | journal = J. Neurochem. | volume = 97 | issue = 5 | pages = 1259–68 | year = 2006 | pmid = 16539653 | doi = 10.1111/j.1471-4159.2006.03782.x }}
- {{cite journal | vauthors = Omura T, Kaneko M, Okuma Y, Orba Y, Nagashima K, Takahashi R, Fujitani N, Matsumura S, Hata A, Kubota K, Murahashi K, Uehara T, Nomura Y | title = A ubiquitin ligase HRD1 promotes the degradation of Pael receptor, a substrate of Parkin | journal = J. Neurochem. | volume = 99 | issue = 6 | pages = 1456–69 | year = 2006 | pmid = 17059562 | doi = 10.1111/j.1471-4159.2006.04155.x | url = http://eprints.lib.hokudai.ac.jp/dspace/bitstream/2115/17141/1/JN99-6-2006.pdf }}
{{refend}}{{G protein-coupled receptors}}{{DEFAULTSORT:Gpr37}}{{transmembranereceptor-stub}} 1 : G protein-coupled receptors |