“Guanidinoacetase”的意思、由来-开放百科全书

词条

Guanidinoacetase

释义

References

{{enzyme
| Name = guanidinoacetase
| EC_number = 3.5.3.2
| CAS_number = 9024-92-4
| IUBMB_EC_number = 3/5/3/2
| GO_code = 0047970
| image =
| width =
| caption =
}}

In enzymology, a guanidinoacetase ({{EC number|3.5.3.2}}) is an enzyme that catalyzes the chemical reaction

guanidinoacetate + H₂O glycine + urea

Thus, the two substrates of this enzyme are guanidinoacetate and H₂O, whereas its two products are glycine and urea.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amidines. The systematic name of this enzyme class is guanidinoacetate amidinohydrolase. This enzyme is also called glycocyaminase. It employs one cofactor, manganese.

References

{{cite journal | vauthors = ROCHE J, LACOMBE G, GIRARD H | date = 1950 | title = [On the specificity of certain bacterial deguanidases generating urea and on arginindihydrolase.] | journal = Biochim. Biophys. Acta | volume = 6 | issue = 1 | pages = 210–6 | pmid = 14791411 | doi = 10.1016/0006-3002(50)90093-x}}
{{cite journal | vauthors = Yorifuji T, Tamai H, Usami H | date = 1977 | title = Purification, crystallization and properties of Mn2+ dependent guanidoacetate amidinohydrolase from a Pseudomonas | journal = Agric. Biol. Chem. | volume = 41 | pages = 959–966 | doi = 10.1271/bbb1961.41.959 | issue = 6 }}

{{Carbon-nitrogen non-peptide hydrolases}}{{Enzymes}}{{Portal bar|Molecular and Cellular Biology|border=no}}{{3.5-enzyme-stub}}

3 : EC 3.5.3|Manganese enzymes|Enzymes of unknown structure

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