| 词条 | Gurmarin |
| 释义 |
| Symbol = Gurmarin | Name = Gurmarin | image = PDB 1gur EBI.jpg | width = | caption = Structure of gurmarin, a sweet taste-suppressing polypeptide.[1] | Pfam= PF11410 | InterPro= IPR010485 | SMART= | Prosite = | SCOP = 1gur | TCDB = | OPM family= 112 | OPM protein= 1c4e | PDB = }}Gurmarin is a 35-residue polypeptide from the Asclepiad vine Gymnema sylvestre (Gurmar). It has been utilised as a pharmacological tool in the study of sweet-taste transduction because of its ability to selectively inhibit the neural response to sweet tastants in rats.[2] As a sweet-taste-suppressing protein, gurmarin is only active on rodent sweet taste receptors but not on that of humans. ref: Appl Microbiol Biotechnol. 2012 Nov;96(3):619-30 References1. ^{{cite journal |vauthors=Arai K, Ishima R, Morikawa S, etal |title=Three-dimensional structure of gurmarin, a sweet taste-suppressing polypeptide |journal=J. Biomol. NMR |volume=5 |issue=3 |pages=297–305 |date=April 1995 |pmid=7787425 |doi= 10.1007/BF00211756|url=}} {{InterPro content|IPR010485}}{{protein-stub}}2. ^{{cite journal |vauthors=Arai K, Aimoto S, Morikawa S, Yoshimura S, Ishima R, Imoto T, Miyasaka A, Akasaka K |title=Three-dimensional structure of gurmarin, a sweet taste-suppressing polypeptide |journal=J. Biomol. NMR |volume=5 |issue=3 |pages=297–305 |year=1995 |pmid=7787425 |doi=10.1007/BF00211756}} 1 : Protein domains |
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