Guy Prendergast may refer to:

• Guy Lenox Prendergast (politician), English MP for Lymington, 1826–27
• Guy Prendergast (cricketer) (1806–1887), English cricketer
• Guy Annesley Prendergast (1834–1919), British Indian Army major-general, son of the above
• Guy Prendergast (British Army officer) (died 1986), British Army officer and Saharan explorer

• Cephoral
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