| 词条 | H1FNT |
| 释义 |
| Name = H1 histone family, member N, testis-specific | caption = | image = | width = | HGNCid = 24893 | Symbol = H1FNT | AltSymbols = HANP1, H1T2 | EntrezGene = 341567 | OMIM = | RefSeq = NM_181788 | UniProt = Q75WM6 | PDB = | ECnumber = | Chromosome = 12 | Arm = q | Band = 13.11 | LocusSupplementaryData = }}H1 histone family, member N, testis-specific is a member of the histone family of nuclear proteins which are a component of chromatin. In humans, this protein is encoded by the H1FNT gene.[1] The H1FNT protein is essential for nuclear formation in spermatozoa, and is involved in the replacement of histones with protamines during spermiogenesis.[2] References1. ^{{cite journal |vauthors=Martianov I, Brancorsini S, Catena R, etal | title = Polar nuclear localization of H1T2, a histone H1 variant, required for spermatid elongation and DNA condensation during spermiogenesis | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 102 | issue = 8 | pages = 2808–13 |date=February 2005 | pmid = 15710904 | pmc = 549447 | doi = 10.1073/pnas.0406060102 | url = | issn = }} 2. ^{{cite journal |vauthors=Tanaka H, Matsuoka Y, Onishi M, Kitamura K, Miyagawa Y, Nishimura H, Tsujimura A, Okuyama A, Nishimune Y | title = Expression profiles and single-nucleotide polymorphism analysis of human HANP1/H1T2 encoding a histone H1-like protein | journal = International Journal of Andrology | volume = 29 | issue = 2 | pages = 353–9 |date=April 2006 | pmid = 16533358 | doi = 10.1111/j.1365-2605.2005.00600.x | url = | issn = }} External links
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