H48 may refer to :

• HMCS Fraser (H48), a 1931 Royal Canadian Navy River-class destroyer
• HMS H48, a 1919 British Royal Navy H class submarine

and also :

• Disorders of optic (2nd) nerve and visual pathways ICD-10 code

• Human Target (TV series)
• Human Target (Vertigo)
• Human T-cell leukaemia virus
• Human T cell leukaemia virus-1
• Human T-cell leukemia virus-1
• Human T-cell leukemia virus type 1
• Human T-cell lymphotropic virus type I
• Human T-cell virus
• Human Technology
• Human Technology (EP)
• Human teeth
• Human teeth sharpening
• Human Television
• Human telomerase reverse transcriptase
• Human telomerase reverse transcriptase gene
• Human terrain system
• Human Terrain Team
• Human Terrain Teams
• Human tetris
• Human Tetris
• Human the death dance
• Human the death dance instrumentals
• Human (The Killers song)
• Human thermoregulation
• Human thighbone trumpet