| 词条 | Hawkinsin |
| 释义 |
| verifiedrevid = 424769488 | ImageFile=Hawkinsin.png | ImageSize=200px | IUPACName= 2-Amino-3-[[2-(carboxymethyl)-2,5-dihydroxy-1-cyclohex-3-enyl]sulfanyl]propanoic acid | OtherNames=(2-L-Cystein-S-yl-1,4-dihydroxycyclohex-5-en-1-yl)acetic acid |Section1={{Chembox Identifiers | CASNo_Ref = {{cascite|correct|??}} | CASNo=63224-90-8 | PubChem=173909 | SMILES=C1C(C=CC(C1SCC(C(=O)O)N)(CC(=O)O)O)O |Section2={{Chembox Properties | Formula=C11H17NO6S | MolarMass=291.32 g/mol | Appearance= | Density= | MeltingPt= | BoilingPt= | Solubility= |Section3={{Chembox Hazards | MainHazards= | FlashPt= | AutoignitionPt = }} Hawkinsin (also known as 2-cystenyl-1,4-dihydroxycyclohexenylacetate[1]) is an amino acid, which is formed after detoxification of a reactive tyrosine metabolite (quinol acetate) by glutathione. Hawkinsin is ninhydrin positive (a common test to detect amino acids and proteins with a free -NH2 group). It is found in elevated concentrations in the urine in hawkinsinuria, which is probably related to the depletion of glutathione and resulting high excretion of 5-oxoproline.[2] References1. ^{{Cite book|url=https://www.worldcat.org/oclc/874142358|title=Physician's guide to the diagnosis, treatment, and follow-up of inherited metabolic diseases|others=Blau, N. (Nenad), 1946-, Duran, Martinus,, Gibson, K. Michael,, Dionisi-Vici, Carlo,|isbn=9783642403378|location=Berlin|oclc=874142358}} {{organic-compound-stub}}2. ^{{Cite book|url=https://www.worldcat.org/oclc/874142358|title=Physician's guide to the diagnosis, treatment, and follow-up of inherited metabolic diseases|others=Blau, N. (Nenad), 1946-, Duran, Martinus,, Gibson, K. Michael,, Dionisi-Vici, Carlo,|isbn=9783642403378|location=Berlin|oclc=874142358}} 3 : Sulfur amino acids|Thioethers|Cyclohexenes |
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