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词条 Helge Stormorken
释义

  1. Research and organisational activity

  2. Career summary

  3. Publications

  4. References

{{BLP sources|date=September 2011}}Helge Stormorken (born 8 October 1922 in Kvam, Gudbrandsdal, Norway) is a Norwegian veterinarian and physician.[1]

Research and organisational activity

He established the cause of a worldwide fatal bleeding disease in piglets leading to its eradication. He described the multifaceted Stormorken syndrome,[2] a mutations in f. VII, f. IX, Fibrinogen Oslo IV and V, all with clinical consequences. Nearly thirty theses on different aspects emanated from the institute together with a host of single papers from its own staff and the many US and European visitors. The most prominent of these was Holm Holmsen who made basic discoveries establishing platelets as secretory non-nucleated cells. Stormorken was active in international organisations within the field, as chairman of the International Society on Thrombosis and Haemostasis 1978–82, as cofounder and member of the governing board in European Thrombosis Research Organisation (ETRO) 1972-78, as an honorary member in 1997. That Oslo, and the institute, was chosen as the site for the first international congress in this field (1971) was a great honour for a country of only four million people.

Stormorken was also the chairman of many committees, local as well as international, a teacher of medical students and other health personnel. He headed the Norwegian Red Cross team and was wounded in the French-Algerian War of 1962. His publications, mainly international, total 260. Now retired, he writes historical essays from his birthplace.

Career summary

Stormorken obtained his veterinary degree at the Norwegian School of Veterinary Science in 1948.[1] He opened a veterinary practice in Otta the next year. He studied in the Medical Faculty, University of Oslo from 1954, and gained a PhD in 1957, with the thesis Comparative Studies on Clotting Mechanisms in Horse, Cow, Dog and Man. He later won the Doctor of Medicine degree in 1958. He was appointed as a professor of animal physiology at the Norwegian School of Veterinary Science in 1959. He moved to the University of Oslo in 1963, as professor and head of the University of Oslo Institute for Thrombosis Research at Rikshospitalet.[3] Then, from 1980 to 1990, he was an assistant professor at Rikshospitalet, and from 1990 to 1995 he worked for the private company Nycomed, mainly within contrast media development. By the time of his 85th birthday he had 275 academic publications.

He was decorated with the Royal Norwegian Order of St. Olav, one of the founders and honorary member of the European Thrombosis Research Organization, Co-chairman and Chairman of the International Society on Thrombosis and Haemostasis, 1978–82, and was a member of several national and international committees. He was visiting professor at Nobel Prize winner C. Heymans Institute in Ghent, Belgium and at The Temple University, Philadelphia. In 1962 he headed the Norwegian Red Cross team to Algeria during the liberation war from France and was wounded in the lower back but recovered. He lives in Sandvika, a suburb of Oslo, but originates from the Gudbrandsdal Valley.

Publications

  • {{cite journal |last1=Peeters |first1=G |last2=Stormorken |first2=H |last3=Vanschoubroek |first3=F |title=The effect of different stimuli on milk ejection and diuresis in the lactating cow |journal=The Journal of Endocrinology |date=April 1960 |volume=20 |issue=2 |pages=163–72 |doi=10.1677/joe.0.0200163 |pmid=14431375}}
  • {{cite journal |last1=Borchgrevink |first1=CF |last2=Egeberg |first2=O |last3=Pool |first3=Judith G |last4=Skulason |first4=T |last5=Stormorken |first5=H |last6=Waaler |first6=B |title=A study of a case of congenital hypoprothrombinaemia |journal=British Journal of Haematology |date=July 1959 |volume=5 |issue=3 |pages=294–301 |doi=10.1111/j.1365-2141.1959.tb04037.x |pmid=13802712}}
  • {{cite journal |last1=Stormorken |first1=H |last2=Svenkerud |first2=R |last3=Slagsvold |first3=P |last4=Lie |first4=H |last5=Lundevall |first5=J |title=Thrombocytopenic bleedings in young pigs due to maternal isoimmunization |journal=Nature |date=15 June 1963 |volume=198 |issue=4885 |pages=1116–1117 |doi=10.1038/1981116b0|bibcode=1963Natur.198.1116S }}
  • {{cite journal |last1=Sjaastad |first1=ØV |last2=Stormorken |first2=H |title=Diet and histamine in the ruminant |journal=Nature |date=2 March 1963 |volume=197 |issue=4870 |pages=907–908 |doi=10.1038/197907a0 |pmid=13977814|bibcode=1963Natur.197..907S }}
  • {{cite journal |last1=Berg |first1=KJ |last2=Skaga |first2=E |last3=Skjaeggestad |first3=O |last4=Stormorken |first4=H |title=Effect of linseed oil on platelet adhesiveness and bleeding-time in patients with coronary heart-disease |journal=Lancet |date=13 November 1965 |volume=2 |issue=7420 |pages=980–2 |doi=10.1016/S0140-6736(65)92842-4 |pmid=4159214}}
  • {{cite journal |last1=Prokopowicz |first1=J |last2=Stormorken |first2=H |title=Fibrinolytic activity of leucocytes in smears of bone marrow and peripheral blood |journal=Scandinavian Journal of Haematology |date=1968 |volume=5 |issue=2 |pages=129–37 |doi=10.1111/j.1600-0609.1968.tb01727.x |pmid=5673825}}
  • {{cite journal |last1=Holmsen |first1=H |last2=Day |first2=HJ |last3=Stormorken |first3=H |title=The blood platelet release reaction |journal=Scandinavian Journal of Haematology. Supplementum |date=1969 |volume=8 |pages=3–26 |doi=10.1111/j.1600-0609.1969.tb01955.x |pmid=4242950}}
  • {{cite journal |last1=Stromorken |first1=H |title=The release reaction of secretion: A general basic phenomenon related to phagocytosis/pinocytosis |journal=Scandinavian Journal of Haematology |date=24 April 2009 |volume=6 |issue=S9 |pages=3–24 |doi=10.1111/j.1600-0609.1969.tb01860.x |pmid=4908841}}
  • {{cite journal |last1=Gjønnæss |first1=H |last2=Stormorken |first2=H |title=Blood clotting, plasma kinins and fibrinolysis |journal=Thrombosis et Diathesis Haemorrhagica |date=31 October 1970 |volume=24 |issue=1 |pages=308–10 |pmid=5483971}}
  • {{cite journal |last1=Kvarstein |first1=B |last2=Stormorken |first2=H |title=Influence of acetylsalicylic acid, butazolidine, colchicine, hydrocortisone, chlorpromazine and imipramine on the phagocytosis of polystyrene latex particles by human leucocytes |journal=Biochemical Pharmacology |date=January 1971 |volume=20 |issue=1 |pages=119–24 |doi=10.1016/0006-2952(71)90477-1 |pmid=5570631}}
  • {{cite journal |last1=Day |first1=HJ |last2=Stormorken |first2=H |last3=Holmsen |first3=H |title=Subcellular localization of platelet factor 3 and platelet factor 4 |journal=Scandinavian Journal of Haematology |date=1973 |volume=10 |issue=4 |pages=254–60 |doi=10.1111/j.1600-0609.1973.tb00069.x |pmid=4797189}}
  • {{cite journal |last1=Dale |first1=J |last2=Myhre |first2=E |last3=Storstein |first3=O |last4=Stormorken |first4=H |title=Proceedings: Arterial thromboembolism and prosthetic heart valves. Effects of acetylsalicylic acid |journal=Thrombosis et Diathesis Haemorrhagica |date=15 November 1975 |volume=34 |issue=2 |pages=587–8 |pmid=1105879}}
  • {{cite journal |last1=Dale |first1=J |last2=Myhre |first2=E |last3=Storstein |first3=O |last4=Stormorken |first4=H |last5=Efskind |first5=L |title=Prevention of arterial thromboembolism with acetylsalicylic acid. A controlled clinical study in patients with aortic ball valves |journal=American Heart Journal |date=July 1977 |volume=94 |issue=1 |pages=101–11 |doi=10.1016/S0002-8703(77)80351-7 |pmid=326013}}
  • {{cite journal |last1=Erikssen |first1=J |last2=Thaulow |first2=E |last3=Stormorken |first3=H |last4=Brendemoen |first4=O |last5=Hellem |first5=A |title=ABO blood groups and coronary heart disease (CHD). A study in subjects with severe and latent CHD |journal=Thrombosis and Haemostasis |date=18 June 1980 |volume=43 |issue=2 |pages=137–40 |pmid=7455973}}
  • {{cite journal |last1=Stormorken |first1=H |last2=Bjørnerud |first2=B |last3=Chye |first3=NE |title=A new constellation: females with concomitant von Willebrand's disease and carriership for factor VIII |journal=Thrombosis Research |date=1 October 1982 |volume=28 |issue=1 |pages=133–6 |doi=10.1016/0049-3848(82)90041-X |pmid=6818709}}
  • {{cite journal |last1=Thaulow |first1=E |last2=Erikssen |first2=J |last3=Myhre |first3=E |last4=Stormorken |first4=H |last5=Hellem |first5=A |title=Platelet function related to the development and presenting symptoms in coronary artery disease. An epidemiological study in apparently healthy men |journal=Scandinavian Journal of Haematology |date=April 1982 |volume=28 |issue=4 |pages=281–8 |doi=10.1111/j.1600-0609.1982.tb00528.x |pmid=7112029}}
  • {{cite journal |last1=Stormorken |first1=H |last2=Brosstad |first2=F |last3=Seim |first3=H |title=A new dysfibrinogenemia: fibrinogen Oslo IV |journal=Thrombosis and Haemostasis |date=28 April 1983 |volume=49 |issue=2 |pages=120–2 |pmid=6868008}}
  • {{cite journal |last1=Gogstad |first1=GO |last2=Stormorken |first2=H |last3=Solum |first3=NO |title=Platelet alpha 2-antiplasmin is located in the platelet alpha-granules |journal=Thrombosis Research |date=15 July 1983 |volume=31 |issue=2 |pages=387–90 |pmid=6636049 |doi=10.1016/0049-3848(83)90339-0}}
  • {{cite journal |last1=Stormorken |first1=H |last2=Gogstad |first2=GO |last3=Brosstad |first3=F |title=Hereditary α2-antiplasmin deficiency |journal=Thrombosis Research |date=August 1983 |volume=31 |issue=4 |pages=647–651 |doi=10.1016/0049-3848(83)90462-0}}
  • Brosstad F, Teige B, Olaisen B, Gravem K, Godal HC & Stormorken H. Two-dimensional electrophoretic characterization (ISO-DALT) of fibrinogen and fibrin subunit chains from four different genetic dysfibrinogen variants. In: Fibrinogen-Structure. Eds. Haverkate et al., de Gruyter & Co, Berlin NB Årstall
  • {{cite journal |last1=Stormorken |first1=H |last2=Gogstad |first2=G |last3=Solum |first3=NO |title=A new bleeding disorder: lack of platelet aggregatory response to adrenaline and lack of secondary aggregation to ADP and platelet activating factor (PAF) |journal=Thrombosis Research |date=15 February 1983 |volume=29 |issue=4 |pages=391–402 |doi=10.1016/0049-3848(83)90242-6 |pmid=6857589}}
  • {{cite journal | last1 = Stormorken | first1 = H | last2 = Erikssen | first2 = J. | year = 1984 | title = xF VIII levels and blood group antigens | url = | journal = Thromb. Haemost. | volume = 51 | issue = | page = 292 }}
  • {{cite journal |last1=Ørstavik |first1=KH |last2=Stormorken |first2=H |last3=Sparr |first3=T |title=Hemophilia BM in a female |journal=Thrombosis Research |date=March 1985 |volume=37 |issue=5 |pages=561–566 |doi=10.1016/0049-3848(85)90088-X |pmid=3983911}}
  • {{cite journal |last1=Stormorken |first1=H |last2=Sjaastad |first2=O |last3=Langslet |first3=A |last4=Sulg |first4=I |last5=Egge |first5=K |last6=Diderichsen |first6=J |title=A new syndrome: thrombocytopathia, muscle fatigue, asplenia, miosis, migraine, dyslexia and ichthyosis |journal=Clinical Genetics |date=November 1985 |volume=28 |issue=5 |pages=367–74 |doi=10.1111/j.1399-0004.1985.tb02209.x |pmid=4085141}}
  • {{cite journal |last1=Thorsen |first1=LI |last2=Brosstad |first2=F |last3=Solum |first3=NO |last4=Stormorken |first4=H |title=Increased binding to ADP-stimulated platelets and aggregation effect of the dysfibrinogen Oslo I as compared with normal fibrinogen |journal=Scandinavian Journal of Haematology |date=February 1986 |volume=36 |issue=2 |pages=203–10 |doi=10.1111/j.1600-0609.1986.tb00829.x |pmid=3010440}}
  • {{cite journal |last1=Stormorken |first1=H |last2=Gjemdal |first2=T |last3=Bjøro |first3=K |title=Lupus anticoagulant: a unique case with lupus anticoagulant and habitual abortion together with antifactor II antibody and bleeding tendency |journal=Gynecologic and Obstetric Investigation |date=1988 |volume=26 |issue=1 |pages=83–8 |doi=10.1159/000293678 |pmid=3139508}}
  • {{cite journal |last1=Stormorken |first1=H |last2=Hessel |first2=B |last3=Lunde |first3=J |last4=Brun Holmsen |first4=I |title=Severe factor viii deficiency in a chromosomally normal female |journal=Thrombosis Research |date=October 1986 |volume=44 |issue=1 |pages=113–117 |doi=10.1016/0049-3848(86)90186-6}}
  • {{cite journal |last1=Schwartz |first1=M. |last2=Mibashan |first2=R.S. |last3=Nicolaides |first3=K.H. |last4=Millar |first4=D.S. |last5=Jenkins |first5=E. |last6=Rodeck |first6=C.H. |last7=rstavik |first7=KarenHelene |last8=Stormorken |first8=H. |title=First-trimester diagnosis of Wiskott-Aldrich syndrome by DNA markers |journal=The Lancet |date=December 1989 |volume=334 |issue=8676 |pages=1405 |doi=10.1016/S0140-6736(89)92026-6 |pmid=2574357}}
  • {{cite journal |last1=Stormorken |first1=H |last2=Hellum |first2=B |last3=Nakstad |first3=B |last4=Thorsrud |first4=AK |last5=Jellum |first5=E |title=Polymorphism of a platelet polypeptide |journal=Thrombosis Research |date=1 October 1990 |volume=60 |issue=1 |pages=71–7 |doi=10.1016/0049-3848(90)90341-9 |pmid=2278037}}
  • {{cite journal |last1=Sjaastad |first1=OV |last2=Blom |first2=AK |last3=Stormorken |first3=H |last4=Nes |first4=N |title=Adenine nucleotides, serotonin, and aggregation properties of platelets of blue foxes (Alopex lagopus) with the Chediak-Higashi syndrome |journal=American Journal of Medical Genetics |date=March 1990 |volume=35 |issue=3 |pages=373–8 |doi=10.1002/ajmg.1320350312 |pmid=2309785}}
  • {{cite journal|last1=Stormorken|first1=H|last2=Briseid|first2=K|last3=Hellum|first3=B|last4=Hoem|first4=NO|last5=Johansen|first5=HT|last6=Ly|first6=B|title=A new case of total kininogen deficiency|journal=Thrombosis Research|date=15 December 1990|volume=60|issue=6|pages=457–67|pmid=2127962|doi=10.1016/0049-3848(90)90230-a}}
  • {{cite journal |last1=Thaulow |first1=E |last2=Erikssen |first2=J |last3=Sandvik |first3=L |last4=Stormorken |first4=H |last5=Cohn |first5=PF |title=Blood platelet count and function are related to total and cardiovascular death in apparently healthy men |journal=Circulation |date=August 1991 |volume=84 |issue=2 |pages=613–7 |doi=10.1161/01.CIR.84.2.613 |pmid=1860204|citeseerx=10.1.1.1007.2808 }}
  • {{cite journal |last1=Pande |first1=Helens |last2=Chester |first2=Alan |last3=Lia |first3=Halldis |last4=Tharsby |first4=Erik |last5=Stormorken |first5=Helge |title=Concomitant occurrence of mucopolysaccharidosis IIIB and Glanzmann's thrombasthenia. Further evidence of a hyperactive ?-N-acetylglucosaminidase-producing allele |journal=Clinical Genetics |date=28 June 2008 |volume=41 |issue=5 |pages=243–247 |doi=10.1111/j.1399-0004.1992.tb03674.x |pmid=1606713}}
  • {{cite journal|last1=Barstad|first1=RM|last2=Stormorken|first2=H|last3=Orning|first3=L|last4=Stephens|first4=RW|last5=Petersen|first5=LB|last6=Kierulf|first6=P|last7=Sakariassen|first7=KS|title=Reduced thrombus formation in native blood of homozygous factor VII-deficient patients at high arterial wall shear rate.|journal=Blood|date=15 November 1994|volume=84|issue=10|pages=3371–7|pmid=7949091}}
  • {{cite journal|last1=Schwartz|first1=M|last2=Békássy|first2=A|last3=Donnér|first3=M|last4=Hertel|first4=T|last5=Hreidarson|first5=S|last6=Kerndrup|first6=G|last7=Stormorken|first7=H|last8=Stokland|first8=T|last9=Tranebjaerg|first9=L|last10=Orstavik|first10=KH|last11=Skovby|first11=F|title=Mutation spectrum in patients with Wiskott-Aldrich syndrome and X-linked thrombocytopenia: identification of twelve different mutations in the WASP gene|journal=Thrombosis and Haemostasis|date=April 1996|volume=75|issue=4|pages=546–50|pmid=8743175}}
  • {{cite journal |last1=Stephens |first1=Ross W. |last2=Örning |first2=Lars |last3=Stormorken |first3=Helge |last4=Hamers |first4=Maria J.A.G. |last5=Petersen |first5=Lizette Balle |last6=Sakariassen |first6=Kjell S. |title=Characterisation of cell-surface procoagulant activities using a microcarrier model |journal=Thrombosis Research |date=December 1996 |volume=84 |issue=6 |pages=453–461 |doi=10.1016/S0049-3848(96)00213-7}}
  • {{cite journal|last1=Brennan|first1=SO|last2=Ridgway|first2=H|last3=Stormorken|first3=H|last4=Brosstad|first4=F|last5=George|first5=PM|title=Characterisation of Fibrinogen Oslo IV by electrospray mass spectrometry|journal=Thrombosis and Haemostasis|date=May 1997|volume=77|issue=5|pages=1040–1|pmid=9184429}}
  • {{cite journal |last1=Kavlie |first1=A |last2=Örning |first2=L |last3=Grindflek |first3=A |last4=Stormorken |first4=H |last5=Prydz |first5=H |title=Characterization of a factor VII molecule carrying a mutation in the second epidermal growth factor-like domain |journal=Thrombosis and Haemostasis |date=1998 |volume=79 |issue=6 |pages=1136–1143 |pmid=9657438}}
  • {{cite journal |last1=Erikssen |first1=G |last2=Liestøl |first2=K |last3=Bjørnholt |first3=JV |last4=Stormorken |first4=H |last5=Thaulow |first5=E |last6=Erikssen |first6=J |title=Erythrocyte sedimentation rate: a possible marker of atherosclerosis and a strong predictor of coronary heart disease mortality |journal=European Heart Journal |date=1 October 2000 |volume=21 |issue=19 |pages=1614–1620 |doi=10.1053/euhj.2000.2148|pmid=10988014 }}

References

1. ^1 {{cite web |last1=Velle |first1=Weiert |title=Helge Stormorken – Norsk biografisk leksikon |url=https://nbl.snl.no/Helge_Stormorken |website=Store norske leksikon |language=no |date=13 February 2009}}
2. ^{{cite web |url=http://www.ashg.org/2009meeting/abstracts/fulltext/f21714.htm |title=Stormorken syndrome: Confirmatory report in a French family. |work=ashg.org |publisher=The American Society of Human Genetics |accessdate=6 September 2011}}
3. ^{{cite journal |last1=Blombäck |first1=Birger |title=Special issue in honor of Professor Helge Stormorken on his 70th birthday |journal=Thrombosis Research |date=1 August 1992 |volume=67 |issue=3 |pages=277–344 |doi=10.1016/0049-3848(92)90002-R |pmid=1476546}}
{{Use dmy dates|date=May 2011}}{{Authority control}}{{DEFAULTSORT:Stormorken, Helge}}

5 : 1922 births|Living people|Norwegian veterinarians|Norwegian School of Veterinary Science faculty|University of Oslo faculty
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