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词条 HL23V
释义

  1. See also

  2. References

  3. Further reading

{{Orphan|date=February 2013}}

HL23V was reputedly a type C RNA tumor virus first isolated in 1975 from cultured human acute myelogenous leukaemia peripheral blood leukocytes, which would have been the first cancer-causing retrovirus isolated from human sera.[1] It was later shown to be a laboratory contaminant of three monkey viruses. The journal Nature, which had published the original research, later retracted the article.

See also

  • Simian sarcoma associated virus (SSAV or SSAV-1), one of two associated viruses comprising HL23V
  • HTLV-1, the actual first human pathogenic retrovirus discovered in 1981

References

1. ^{{Cite journal|journal = Nature|title = Characterisation of a virus (HL23V) isolated from cultured acute myelogenous leukaemic cells|last8 = Gallagher|last7 = Gallo|volume = 260|issue = 5548|pmid = 176596|year = 1976|pages = 266–268|doi = 10.1038/260266a0|last6 = Spiegelman|last2 = Peters|last1 = Chan|last3 = Sweet|last4 = Ohno|last5 = Kufe | first1 = E. | first2 = W. | first3 = R. | first4 = T. | first5 = D. | first6 = S. | first7 = R. | first8 = R.|bibcode = 1976Natur.260..266C }}; {{Cite journal | year = 1975 | pages = 350–3 | pmid = 46123 | doi = 10.1126/science.46123| issue = 4174 | volume = 187 | last2 = Gallo | first1 = R. | first2 = R. | title = Type C RNA tumor virus isolated from cultured human acute myelogenous leukemia cells | journal = Science | last1 = Gallagher|bibcode = 1975Sci...187..350G }}

Further reading

  • Science Fictions: A Scientific Mystery, a Massive Cover-up, and the Dark Legacy of Robert Gallo {{ISBN|0316090042}}, 2002, John Crewdson
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3 : RNA viruses|Medical error|Controversial taxa

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