“HLA-B54”的意思、由来-开放百科全书

词条

HLA-B54

释义

Serotype
Allele distribution
See also
References




major histocompatibility complex (human), class I, B54
Alleles	B*5401
Structure (See HLA-B)
Symbol(s)	[https://web.archive.org/web/20070821210135/http://www.gene.ucl.ac.uk/nomenclature/data/get_data.php?hgnc_id=4932 HLA-B]
EBI-HLA	B*5401
Locus	chr.6 [https://www.ncbi.nlm.nih.gov/Omim/getmap.cgi?chromosome=6p21.31 6p21.31]

HLA-B54 (B54) is an HLA-B serotype. B54 is a split antigen from the B22 broad antigen, sister serotypes are B55 and B56.^[1] The serotype identifies the more common HLA-B*55 gene products.^[2]

Serotype

B54 and B22 serotype recognition of HLA B*5401 allele^[3]
B*54	B54	B22	Sample
allele	%	%	size (N)
5401	67	3	631

Allele distribution

**HLA B*5401 frequencies**
freq
ref.	Population	(%)
^[4]	USA Hawaii Okinawa	10.6
^[4]	Japan Central	7.7
^[4]	South Korea (3)	5.9
^[4]	China Guangzhou	4.5
^[4]	Thailand (3)	4.1
^[4]	China Inner Mongolia	3.4
^[4]	China North Han	3.3
^[4]	China Beijing Shijiazhuang Tianjian Han	3.0
^[4]	China South Han	2.5
^[4]	Russia Tuva pop 2	2.2
^[4]	China Guangxi Maonan	1.9
^[4]	Thailand	1.8
^[4]	Taiwan Thao	1.7
^[4]	China Tibet Autonomous Region Tibetans	1.3

References

1. ^{{cite journal |vauthors=Hildebrand WH, Madrigal JA, Little AM, Parham P | title = HLA-Bw22: a family of molecules with identity to HLA-B7 in the alpha 1-helix | journal = J. Immunol. | volume = 148 | issue = 4 | pages = 1155–62 | year = 1992 | pmid = 1737933 | doi = }}
2. ^{{cite journal |vauthors=Marsh SG, Albert ED, Bodmer WF, etal | title = Nomenclature for factors of the HLA system, 2004 | journal = Tissue Antigens | volume = 65 | issue = 4 | pages = 301–69 | year = 2005 | pmid = 15787720 | pmc = 2396006 | doi = 10.1111/j.1399-0039.2005.00379.x }}
3. ^derived from IMGT/HLA
4. ^¹²³⁴⁵⁶⁷⁸⁹¹⁰¹¹¹²¹³{{cite journal |vauthors=Middleton D, Menchaca L, Rood H, Komerofsky R | title = New allele frequency database: http://www.allelefrequencies.net | journal = Tissue Antigens | volume = 61 | issue = 5 | pages = 403–7 | year = 2003 | pmid = 12753660 | doi =10.1034/j.1399-0039.2003.00062.x }}

1 : HLA-B alleles

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Serotype

Allele distribution

See also

References