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词条 HLA-B56
释义

  1. Serotype

  2. Allele distribution

  3. References

major histocompatibility complex (human), class I, B56
AllelesB*5601, *5602, *5603, *5604
Structure (See HLA-B)
Symbol(s)[https://web.archive.org/web/20070821210135/http://www.gene.ucl.ac.uk/nomenclature/data/get_data.php?hgnc_id=4932 HLA-B]
EBI-HLAB*5601
B*5602
B*5603
B*5604
Locuschr.6 [https://www.ncbi.nlm.nih.gov/Omim/getmap.cgi?chromosome=6p21.31 6p21.31]

HLA-B56 (B56) is an HLA-B serotype. B56 is a split antigen from the B22 broad antigen, sister serotypes are B54 and B55. The serotype identifies the more common HLA-B*56 gene products.[1] (For terminology help see: HLA-serotype tutorial)

Serotype

B56 and B22 serotype recognition of Some HLA B*56 allele-group gene products[2]
B*56B56B22Sample
allele % % size (N)
5601 72 5 671
5603 46 8 13
5604 73 11

Allele distribution

HLA B*5601 frequencies
freq
ref. Population(%)
[3] Australian Aborigine Kimberly35.5
[3] Papua New Guinea Madang34.6
[3] Papua New Guinea New Britain Rabaul31.6
[3] Taiwan Ami20.4
[3] New Caledonia19.2
[3] Australian Aborigine Groote Eylandt18.0
[3] Australian Aborigine Cape York Peninsula16.5
[3] Australian Aborigine Yuendumu11.4
[3] China Yunnan Lisu9.4
[3] China Yunnan Nu3.8
[3] Senegal Niokholo Mandenka2.7
[3] Sudanese2.5
[3] American Samoa2.0
[3] China Guangxi Maonan1.9
[3] Taiwan Hakka1.8
[3] Thailand1.8
[3] Finland1.7
[3] Georgia Tibilisi Kurds1.7
[3] India Andhra Pradesh Golla1.4
[3] Croatia1.3
[3] Japan (5)1.3
[3] South Africa Natal Tamil1.0
[3] Taiwan Rukai1.0

References

1. ^{{cite journal |vauthors=Marsh SG, Albert ED, Bodmer WF, etal | title = Nomenclature for factors of the HLA system, 2004 | journal = Tissue Antigens | volume = 65 | issue = 4 | pages = 301–69 | year = 2005 | pmid = 15787720 | doi = 10.1111/j.1399-0039.2005.00379.x }}
2. ^derived from IMGT/HLA
3. ^10 11 12 13 14 15 16 17 18 19 20 21 22 {{cite journal |vauthors=Middleton D, Menchaca L, Rood H, Komerofsky R | title = New allele frequency database: http://www.allelefrequencies.net | journal = Tissue Antigens | volume = 61 | issue = 5 | pages = 403–7 | year = 2003 | pmid = 12753660 | doi =10.1034/j.1399-0039.2003.00062.x }}
{{HLA-B serotypes}}{{DEFAULTSORT:Hla-B56}}

1 : HLA-B alleles

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