释义 |
- Serotype
- Alleles
- References
| HLA-B (alpha)-β2MG with bound peptide | major histocompatibility complex (human), class I, B70 | Alleles | *1503, *1509, *1510, *1518, *1529, *1537 | Structure (See HLA-B) | Shared data | Locus | chr.6 [https://www.ncbi.nlm.nih.gov/Omim/getmap.cgi?chromosome=6p21.31 6p21.31] | HLA-B70 (B70) is an HLA-B serotype. The serotype identifies certain B*15 gene-allele protein products of HLA-B.[1]B70 is one of many split antigens of the broad antigen, B15. Serotype Serotypes B15, B62, B63, B70, B71, B72, B75, B76, B77 recognition of the HLA B*15 gene products[2]B*15 | B15 | B62 | B63 | B70 | B71 | B72 | B75 | B76 | B77 | Sample | allele | % | % | % | % | % | % | % | % | % | size (N) | {{HBA|1503}} | 1 | 61 | 10 | 2569 | {{HBA|1509}} | 53 | 65 | {{HBA|1510}} | 1 | 49 | 2 | 2 | 1 | 1204 | {{HBA|1518}} | 51 | 3 | 552 | {{HBA|1529}} | 19 | 21 | {{HBA|1537}} | 30 | 34 | Alleles link-out to IMGT/HLA Databease at EBI | {{clear|left}}Alleles HLA B*1503 frequencies freq | ref. | Population | (%) | [3] | Burkina Faso Rimaibe | 13.8 | Guinea Bissau | 10.8 | Cameroon Pygmy Baka | 10.0 | South African Natal Zulu | 9.5 | Kenya Luo | 8.9 | Ivory Coast Akan Adiopodoume | 8.0 | Kenya Nandi | 7.9 | Cameroon Sawa | 7.7 | Zimbabwe Harare Shona | 7.7 | USA African America | 7.3 | Burkina Faso Fulani | 7.1 | Mali Bandiagara | 6.9 | Senegal Niokholo Mandenka | 6.9 | Cape Verde SE Islands | 6.5 | Kenya | 6.3 | Uganda Kampala | 6.2 | Sudanese | 6.0 | Zambia Lusaka | 5.7 | Cameroon Yaounde | 4.9 | Cape Verde NW Islands | 4.8 | Oman | 4.7 | Cameroon Bamileke | 4.5 | Tunisia Tunis | 4.5 | Cameroon Beti | 3.7 | Brazil Belo Horizonte | 3.2 | Azores Terceira Island | 2.4 | Madeira | 2.2 | Saudi Arabia Guraiat and Hail | 2.0 | Tunisia | 2.0 | United Arab Emerates | 1.5 | Brazil | 1.4 | Cuban White | 1.4 | Morocco Nador Metalsa | 1.4 | Mexico Mestizos | 1.2 | Italy Bergamo | 1.1 | Portugal North | 1.1 | American Samoa | 1.0 | Iran Baloch | 1.0 | Mexico Guadalajara Mestizos (2) | 1.0 | Azores Central Islands | 0.9 | Israel Ashk. and Non-Ashk. Jews | 0.9 | Taiwan Hakka | 0.9 | Croatia | 0.7 | {{clear|right}} HLA B*1509 frequencies freq | ref. | Population | (%) | [3] | Burkina Faso Fulani | 4.1 | India West Coast Parsis | 3.0 | Spain Eastern Andalusia Gipsy | 3.0 | Mexico Mestizos | 2.4 | Italy South Campania | 1.2 | Burkina Faso Rimaibe | 1.1 | China Inner Mongolia | 1.0 | Mali Bandiagara | 0.7 | Czech Republic | 0.5 | {{clear|right}} HLA B*1510 frequencies freq | ref. | Population | (%) | [3] | South African Natal Zulu | 8.5 | Zimbabwe Harare Shona | 8.4 | Ivory Coast Akan Adiopodoume | 5.7 | Kenya | 5.2 | Zambia Lusaka | 4.6 | Cameroon Sawa | 3.8 | Guinea Bissau | 3.8 | Kenya Luo | 3.6 | Senegal Niokholo Mandenka | 3.2 | Cameroon Beti | 2.8 | USA African Americans (3) | 2.7 | Uganda Kampala | 2.5 | Mexico Mestizos | 2.4 | Mali Bandiagara | 2.2 | Kenya Nandi | 1.7 | Brazil Belo Horizonte | 1.6 | Cameroon Bamileke | 1.3 | Cuban Mulatto | 1.2 | Cameroon Yaounde | 1.1 | Iran Baloch | 1.0 | Sudanese | 1.0 | Tunisia | 1.0 | Brazil Terena | 0.9 | Cape Verde NW Islands | 0.8 | United Arab Emerates | 0.8 | USA North American Natives | 0.8 | Guadalajara Mestizos (2) | 0.5 | {{clear|left}} HLA B*1518 frequencies freq | ref. | Population | (%) | [3] | South Africa Natal Tamil | 4.1 | Autonomous Tibetans | 3.8 | India Mumbai Marathas | 3.7 | China North Han | 2.9 | USA Hawaii Okinawa | 2.9 | China Guangzhou Han | 2.4 | India Andhra Pradesh Golla | 2.4 | China Beijing | 2.3 | Taiwan Hakka | 1.8 | Japan | 1.7 | India North Delhi | 1.6 | China Inner Mongolia | 1.5 | China Qinghai Hui | 1.4 | Czech Republic | 1.4 | China Yunnan Nu | 1.3 | Shijiazhuang Tianjian Han | 1.1 | Ivory Coast Akan Adiopodoume | 1.1 | Senegal Niokholo Mandenka | 1.1 | Zambia Lusaka | 1.1 | Portugal Centre | 1.0 | Singapore Javanese Indonesians | 1.0 | Thailand (3) | 1.0 | South Korea (3) | 0.9 | Cape Verde Islands | 0.8 | France South East | 0.8 | Guinea Bissau | 0.8 | China South Han | 0.7 | China Yunnan Lisu | 0.7 | Russia Tuva (2) | 0.6 | Singapore Chinese Han | 0.6 | Spain Eastern Andalusia | 0.6 | References1. ^{{cite journal |vauthors=Marsh SG, Albert ED, Bodmer WF, etal | title = Nomenclature for factors of the HLA system, 2004 | journal = Tissue Antigens | volume = 65 | issue = 4 | pages = 301–69 | year = 2005 | pmid = 15787720 | pmc = 2396006 | doi = 10.1111/j.1399-0039.2005.00379.x }} 2. ^derived from IMGT/HLA 3. ^1 2 3 {{cite journal |vauthors=Middleton D, Menchaca L, Rood H, Komerofsky R | title = New allele frequency database: http://www.allelefrequencies.net | journal = Tissue Antigens | volume = 61 | issue = 5 | pages = 403–7 | year = 2003 | pmid = 12753660 | doi =10.1034/j.1399-0039.2003.00062.x }}
{{HLA-B serotypes}} 1 : HLA-B*15 serotypes |