Holborne may refer to:

• Anthony Holborne (1545–1602), composer of English consort music during the reign of Queen Elizabeth I
• James Holborne of Menstrie, Scottish soldier during the years of the English Civil War
• Robert Holborne (died 1647), lawyer, Member of Parliament, attorney-general to Prince of Wales, knighted 1643
• William Holborne, officer on the flagship of Admiral Sir Edward Hawke, the Kent, in 1747

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