词条 | Hydrazine (antidepressant) |
释义 |
The hydrazine antidepressants are a group of non-selective, irreversible monoamine oxidase inhibitors (MAOIs) which were discovered and initially marketed in the 1950s and 1960s. Most have been withdrawn due to toxicity, namely hepatotoxicity, but a few still remain in clinical use. Tranylcypromine, a structurally unrelated MAOI introduced around the same time as the hydrazines, was originally advertised as non-hydrazine as a result of its diminished propensity for causing hepatotoxicity. List of hydrazine antidepressantsMarketed{{colbegin}}
Legend: ‡ = Withdrawn from the market; † = Partially discontinued; Bolded names indicate major drugs. Never marketed
Parkinson's
Tranquillosedative
References
4 : Hepatotoxins|Hydrazines|Monoamine oxidase inhibitors|Withdrawn drugs |
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