“Hydroxylysine kinase”的意思、由来-开放百科全书

词条

Hydroxylysine kinase

释义

References

{{enzyme
| Name = hydroxylysine kinase
| EC_number = 2.7.1.81
| CAS_number = 9073-58-9
| IUBMB_EC_number = 2/7/1/81
| GO_code = 0047992
| image =
| width =
| caption =
}}

In enzymology, a hydroxylysine kinase ({{EC number|2.7.1.81}}) is an enzyme that catalyzes the chemical reaction

GTP + 5-hydroxy-L-lysine GDP + 5-phosphonooxy-L-lysine

Thus, the two substrates of this enzyme are GTP and 5-hydroxy-L-lysine, whereas its two products are GDP and 5-phosphonooxy-L-lysine.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is GTP:5-hydroxy-L-lysine O-phosphotransferase. Other names in common use include hydroxylysine kinase (phosphorylating), and guanosine triphosphate:5-hydroxy-L-lysine O-phosphotransferase. This enzyme participates in lysine degradation.

References

{{cite journal | vauthors = Hiles RA, Henderson LM | date = 1972 | title = The partial purification and properties of hydroxylysine kinase from rat liver | journal = J. Biol. Chem. | volume = 247 | pages = 646–51 | pmid = 4621658 | issue = 3 }}

2 : EC 2.7.1|Enzymes of unknown structure

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