I72 can refer to:

• Interstate 72
• HMS Unicorn (I72)
• Westfield Airport

• The Deaf Mute
• The Deal (album)
• The Deal (BET TV series)
• The Dealer from Amsterdam
• The Dealer (Stevie Nicks Song)
• The Deaner Album
• The Dean Ween Album
• The Dear Jack Foundation
• The Dearly Beloved (band)
• The Death Agony of the Eagles
• The Death and Life of John F. Donovan
• The Death and Life of Marsha P. Johnson
• The Death and Life of Otto Bloom
• The Death Cure (film)
• TheDeath Cure (film)
• The Death Dance (film)
• The Deathhead Virgin
• The Death House
• The Death Note
• The Death Notebooks
• The death of a cyclist
• The Death of Adolf Hitler
• The Death of Adonis (Mazzuoli)
• The Death of Adonis (Rodin)
• The Death of a Government Clerk