| 词条 | Iberogast |
| 释义 |
Iberogast is a mixture of extracts from bitter candytuft (Iberis amara), angelica root (Angelicae radix), milk thistle fruit (Silybi mariani fructus), celandine herb (Chelidonium majus), caraway fruit (Carvi fructus), liquorice root (Liquiritiae radix), peppermint herb (Menthae piperitae folium), balm leaf (Melissae folium) and chamomile flower (Matricariae flos).[2] Medical usesA 2004 meta-analysis comprising three randomized placebo-controlled studies with a total of 173 patients suggested that iberogast was more effective than placebo in relieving "the most bothersome gastrointestinal symptom" of functional dyspepsia as identified by each patient. Additionally, a single reference-controlled study was discussed, comparing iberogast to the prokinetic cisapride in the treatment of "'functional dyspepsia of the dysmotility type'" and finding no significant differences in efficacy or tolerability. This paper noted that, while iberogast seems to consistently provide symptomatic relief to patients, its efficacy is more evident "with associated symptoms of gastro-oesophageal reflux or predominance of epigastric pain." It suggests a synergy of therapeutic mechanisms provided by the complex interactions between the GI tract and each individual component of iberogast. It also supports a promising safety profile for the formulation, but notes that its results must be confirmed in larger studies in order to provide any recommendations regarding the efficacy or safety of iberogast in the treatment of functional dyspepsia.[3] References1. ^{{cite journal |vauthors=Wegener T, Wagner H | title = The active components and the pharmacological multi-target principle of STW 5 (Iberogast) | journal = Phytomedicine | volume = 13 | issue = Suppl 5 | pages = 20–35 | year = 2006 | pmid = 16926095 | doi = 10.1016/j.phymed.2006.07.001 }} 2. ^{{cite journal |vauthors=Saller R, Pfister-Hotz G, Iten F, Melzer J, Reichling J | title = [Iberogast: a modern phytotherapeutic combined herbal drug for the treatment of functional disorders of the gastrointestinal tract (dyspepsia, irritable bowel syndrome)--from phytomedicine to "evidence based phytotherapy". A systematic review] | language = German | journal = Forschende Komplementärmedizin und Klassische Naturheilkunde | volume = 9 | issue = Suppl 1 | pages = 1–20 | year = 2002 | pmid = 12618546 | doi = 10.1159/000068645 }} 3. ^{{cite journal|vauthors=Melzer J, Rösch W, Reichling J, Brignoli R, Saller R|year=2004|title=Meta-analysis: phytotherapy of functional dyspepsia with the herbal drug preparation STW 5 (Iberogast)|journal=Alimentary Pharmacology and Therapeutics|volume=20|issue=11–12|pages=1279–87|doi=10.1111/j.1365-2036.2004.02275.x|pmid=15606389}} External links
2 : Pharmacognosy|Phytochemicals |
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