| 释义 |
- References
- Further reading
- External links
{{Infobox_gene}}ICOS ligand is a protein that in humans is encoded by the ICOSLG gene.[1][2][3] ICOSLG has also been designated as CD275 (cluster of differentiation 275). References 1. ^{{cite journal | vauthors = Ishikawa K, Nagase T, Suyama M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O | title = Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro | journal = DNA Research | volume = 5 | issue = 3 | pages = 169–76 | date = June 1998 | pmid = 9734811 | pmc = | doi = 10.1093/dnares/5.3.169 }}
2. ^{{cite journal | vauthors = Yoshinaga SK, Zhang M, Pistillo J, Horan T, Khare SD, Miner K, Sonnenberg M, Boone T, Brankow D, Dai T, Delaney J, Han H, Hui A, Kohno T, Manoukian R, Whoriskey JS, Coccia MA | title = Characterization of a new human B7-related protein: B7RP-1 is the ligand to the co-stimulatory protein ICOS | journal = International Immunology | volume = 12 | issue = 10 | pages = 1439–47 | date = October 2000 | pmid = 11007762 | pmc = | doi = 10.1093/intimm/12.10.1439 }}
3. ^{{cite web | title = Entrez Gene: ICOSLG inducible T-cell co-stimulator ligand| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=23308| accessdate = }}
Further reading {{refbegin | 2}}- {{cite journal | vauthors = Flesch IE | title = Inducible costimulator-ligand (ICOS-L) | journal = Journal of Biological Regulators and Homeostatic Agents | volume = 16 | issue = 3 | pages = 217–9 | year = 2003 | pmid = 12456022 | doi = }}
- {{cite journal | vauthors = Ling V, Wu PW, Finnerty HF, Bean KM, Spaulding V, Fouser LA, Leonard JP, Hunter SE, Zollner R, Thomas JL, Miyashiro JS, Jacobs KA, Collins M | title = Cutting edge: identification of GL50, a novel B7-like protein that functionally binds to ICOS receptor | journal = Journal of Immunology | volume = 164 | issue = 4 | pages = 1653–7 | date = February 2000 | pmid = 10657606 | doi = 10.4049/jimmunol.164.4.1653 }}
- {{cite journal | vauthors = Aicher A, Hayden-Ledbetter M, Brady WA, Pezzutto A, Richter G, Magaletti D, Buckwalter S, Ledbetter JA, Clark EA | title = Characterization of human inducible costimulator ligand expression and function | journal = Journal of Immunology | volume = 164 | issue = 9 | pages = 4689–96 | date = May 2000 | pmid = 10779774 | doi = 10.4049/jimmunol.164.9.4689 }}
- {{cite journal | vauthors = Wang S, Zhu G, Chapoval AI, Dong H, Tamada K, Ni J, Chen L | title = Costimulation of T cells by B7-H2, a B7-like molecule that binds ICOS | journal = Blood | volume = 96 | issue = 8 | pages = 2808–13 | date = October 2000 | pmid = 11023515 | doi = }}
- {{cite journal | vauthors = Ling V, Wu PW, Miyashiro JS, Marusic S, Finnerty HF, Collins M | title = Differential expression of inducible costimulator-ligand splice variants: lymphoid regulation of mouse GL50-B and human GL50 molecules | journal = Journal of Immunology | volume = 166 | issue = 12 | pages = 7300–8 | date = June 2001 | pmid = 11390480 | doi = 10.4049/jimmunol.166.12.7300 }}
- {{cite journal | vauthors = Sperling AI, Bluestone JA | title = ICOS costimulation: It's not just for TH2 cells anymore | journal = Nature Immunology | volume = 2 | issue = 7 | pages = 573–4 | date = July 2001 | pmid = 11429535 | doi = 10.1038/89709 }}
- {{cite journal | vauthors = Wang S, Zhu G, Tamada K, Chen L, Bajorath J | title = Ligand binding sites of inducible costimulator and high avidity mutants with improved function | journal = The Journal of Experimental Medicine | volume = 195 | issue = 8 | pages = 1033–41 | date = April 2002 | pmid = 11956294 | pmc = 2193694 | doi = 10.1084/jem.20011607 }}
- {{cite journal | vauthors = Khayyamian S, Hutloff A, Büchner K, Gräfe M, Henn V, Kroczek RA, Mages HW | title = ICOS-ligand, expressed on human endothelial cells, costimulates Th1 and Th2 cytokine secretion by memory CD4+ T cells | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 99 | issue = 9 | pages = 6198–203 | date = April 2002 | pmid = 11983910 | pmc = 122926 | doi = 10.1073/pnas.092576699 }}
- {{cite journal | vauthors = Akbari O, Freeman GJ, Meyer EH, Greenfield EA, Chang TT, Sharpe AH, Berry G, DeKruyff RH, Umetsu DT | title = Antigen-specific regulatory T cells develop via the ICOS-ICOS-ligand pathway and inhibit allergen-induced airway hyperreactivity | journal = Nature Medicine | volume = 8 | issue = 9 | pages = 1024–32 | date = September 2002 | pmid = 12145647 | doi = 10.1038/nm745 }}
- {{cite journal | vauthors = Kurosawa S, Myers AC, Chen L, Wang S, Ni J, Plitt JR, Heller NM, Bochner BS, Schleimer RP | title = Expression of the costimulatory molecule B7-H2 (inducible costimulator ligand) by human airway epithelial cells | journal = American Journal of Respiratory Cell and Molecular Biology | volume = 28 | issue = 5 | pages = 563–73 | date = May 2003 | pmid = 12707012 | doi = 10.1165/rcmb.2002-0199OC }}
- {{cite journal | vauthors = Chen XL, Cao XD, Kang AJ, Wang KM, Su BS, Wang YL | title = In situ expression and significance of B7 costimulatory molecules within tissues of human gastric carcinoma | journal = World Journal of Gastroenterology | volume = 9 | issue = 6 | pages = 1370–3 | date = June 2003 | pmid = 12800259 | doi = 10.3748/wjg.v9.i6.1370}}
- {{cite journal | vauthors = Iwai H, Abe M, Hirose S, Tsushima F, Tezuka K, Akiba H, Yagita H, Okumura K, Kohsaka H, Miyasaka N, Azuma M | title = Involvement of inducible costimulator-B7 homologous protein costimulatory pathway in murine lupus nephritis | journal = Journal of Immunology | volume = 171 | issue = 6 | pages = 2848–54 | date = September 2003 | pmid = 12960306 | doi = 10.4049/jimmunol.171.6.2848 }}
- {{cite journal | vauthors = Schreiner B, Wischhusen J, Mitsdoerffer M, Schneider D, Bornemann A, Melms A, Tolosa E, Weller M, Wiendl H | author-link9 = Heinz Wiendl | title = expression of the B7-related molecule ICOSL by human glioma cells in vitro and in vivo | journal = Glia | volume = 44 | issue = 3 | pages = 296–301 | date = December 2003 | pmid = 14603470 | doi = 10.1002/glia.10291 }}
- {{cite journal | vauthors = Saatian B, Yu XY, Yu X, Lane AP, Doyle T, Casolaro V, Spannhake EW | title = Expression of genes for B7-H3 and other T cell ligands by nasal epithelial cells during differentiation and activation | journal = American Journal of Physiology. Lung Cellular and Molecular Physiology | volume = 287 | issue = 1 | pages = L217-25 | date = July 2004 | pmid = 15047568 | doi = 10.1152/ajplung.00132.2003 }}
- {{cite journal | vauthors = Nakazawa A, Dotan I, Brimnes J, Allez M, Shao L, Tsushima F, Azuma M, Mayer L | title = The expression and function of costimulatory molecules B7H and B7-H1 on colonic epithelial cells | journal = Gastroenterology | volume = 126 | issue = 5 | pages = 1347–57 | date = May 2004 | pmid = 15131796 | doi = 10.1053/j.gastro.2004.02.004 }}
{{refend}} External links - {{MeshName|ICOSLG+protein,+human}}
{{B7 family}}{{Clusters of differentiation}}{{membrane-protein-stub}} 1 : Clusters of differentiation |