| 词条 | Indium (111In) biciromab |
| 释义 |
| Verifiedfields = changed | verifiedrevid = 458273546 | drug_name = Indium (111In) biciromab | type = mab | mab_type = Fab' | source = o | target = Fibrin II, beta chain | tradename = FibriScint | pregnancy_AU = | pregnancy_US = | pregnancy_category = N/A | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = Withdrawn | routes_of_administration = | bioavailability = | protein_bound = | metabolism = | elimination_half-life = | excretion = | ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}} | ChemSpiderID = none | CAS_number_Ref = {{cascite|changed|??}} | CAS_number = 138783-13-8 | ATC_prefix = none | ATC_suffix = | PubChem = | DrugBank_Ref = {{drugbankcite|correct|drugbank}} | DrugBank = | KEGG_Ref = {{keggcite|correct|kegg}} | KEGG = D03111 | chemical_formula = | molecular_weight = }}Indium (111In) biciromab (INN, trade name FibriScint, developed by Centocor) was a drug targeting fibrin, a protein involved in the clotting of blood.[1] It was the Fab' fragment of a mouse monoclonal antibody labelled with the radioisotope indium-111 for the diagnosis of thromboembolism,[2] but was withdrawn during clinical trials.[3] References1. ^{{cite journal|last=King|first=David J.|author2=John R. Adair|year=1999|title=Recombinant antibodies for the diagnosis and therapy of human disease|journal=Current Opinion in Drug Discovery & Development|volume=2|issue=2|page=112|issn=1367-6733}} {{Monoclonals for bone, musculoskeletal, circulatory, and neurologic systems}}{{monoclonal-antibody-stub}}2. ^Answers.com: Centocor Ortho Biotech Products, L.P. 3. ^DiagnosticImaging.com: Centocor withdraws imaging agent applications 1 : Janssen Biotech |
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