| 释义 |
- References
- Further reading
- External links
{{Infobox_gene}}Integrin alpha-8 is a protein that in humans is encoded by the ITGA8 gene.[1][2]{{PBB_Summary
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}}References1. ^{{cite journal |vauthors=Schnapp LM, Breuss JM, Ramos DM, Sheppard D, Pytela R | title = Sequence and tissue distribution of the human integrin alpha 8 subunit: a beta 1-associated alpha subunit expressed in smooth muscle cells | journal = J Cell Sci | volume = 108 | issue = 2| pages = 537–44 |date=Jul 1995 | pmid = 7768999 | pmc = | doi = }}
2. ^{{cite web | title = Entrez Gene: ITGA8 integrin, alpha 8| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8516| accessdate = }}
Further reading{{refbegin | 2}}- {{cite journal |vauthors=Schnapp LM, Hatch N, Ramos DM, etal |title=The human integrin alpha 8 beta 1 functions as a receptor for tenascin, fibronectin, and vitronectin. |journal=J. Biol. Chem. |volume=270 |issue= 39 |pages= 23196–202 |year= 1995 |pmid= 7559467 |doi=10.1074/jbc.270.39.23196 }}
- {{cite journal |vauthors=Denda S, Müller U, Crossin KL, etal |title=Utilization of a soluble integrin-alkaline phosphatase chimera to characterize integrin alpha 8 beta 1 receptor interactions with tenascin: murine alpha 8 beta 1 binds to the RGD site in tenascin-C fragments, but not to native tenascin-C. |journal=Biochemistry |volume=37 |issue= 16 |pages= 5464–74 |year= 1998 |pmid= 9548928 |doi= 10.1021/bi9727489 | pmc=2710129 }}
- {{cite journal |vauthors=Hartner A, Schöcklmann H, Pröls F, etal |title=Alpha8 integrin in glomerular mesangial cells and in experimental glomerulonephritis. |journal=Kidney Int. |volume=56 |issue= 4 |pages= 1468–80 |year= 1999 |pmid= 10504498 |doi= 10.1046/j.1523-1755.1999.00662.x }}
- {{cite journal |vauthors=Littlewood Evans A, Müller U |title=Stereocilia defects in the sensory hair cells of the inner ear in mice deficient in integrin alpha8beta1. |journal=Nat. Genet. |volume=24 |issue= 4 |pages= 424–8 |year= 2000 |pmid= 10742111 |doi= 10.1038/74286 }}
- {{cite journal |vauthors=Brandenberger R, Schmidt A, Linton J, etal |title=Identification and characterization of a novel extracellular matrix protein nephronectin that is associated with integrin alpha8beta1 in the embryonic kidney. |journal=J. Cell Biol. |volume=154 |issue= 2 |pages= 447–58 |year= 2001 |pmid= 11470831 |doi=10.1083/jcb.200103069 | pmc=2150762 }}
- {{cite journal |vauthors=Ljubimov AV, Saghizadeh M, Pytela R, etal |title=Increased expression of tenascin-C-binding epithelial integrins in human bullous keratopathy corneas. |journal=J. Histochem. Cytochem. |volume=49 |issue= 11 |pages= 1341–50 |year= 2001 |pmid= 11668187 |doi= 10.1177/002215540104901102}}
- {{cite journal |vauthors=Valerius MT, Patterson LT, Feng Y, Potter SS |title=Hoxa 11 is upstream of Integrin alpha8 expression in the developing kidney. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 12 |pages= 8090–5 |year= 2002 |pmid= 12060755 |doi= 10.1073/pnas.122229199 | pmc=123025 }}
- {{cite journal |vauthors=Lu M, Munger JS, Steadele M, etal |title=Integrin alpha8beta1 mediates adhesion to LAP-TGFbeta1. |journal=J. Cell Sci. |volume=115 |issue= Pt 23 |pages= 4641–8 |year= 2003 |pmid= 12415008 |doi=10.1242/jcs.00145 }}
- {{cite journal |vauthors=Bieritz B, Spessotto P, Colombatti A, etal |title=Role of alpha8 integrin in mesangial cell adhesion, migration, and proliferation. |journal=Kidney Int. |volume=64 |issue= 1 |pages= 119–27 |year= 2004 |pmid= 12787402 |doi= 10.1046/j.1523-1755.2003.00057.x }}
- {{cite journal |vauthors=Deloukas P, Earthrowl ME, Grafham DV, etal |title=The DNA sequence and comparative analysis of human chromosome 10. |journal=Nature |volume=429 |issue= 6990 |pages= 375–81 |year= 2004 |pmid= 15164054 |doi= 10.1038/nature02462 }}
- {{cite journal |vauthors=Ekwa-Ekoka C, Diaz GA, Carlson C, etal |title=Genomic organization and sequence variation of the human integrin subunit alpha8 gene (ITGA8). |journal=Matrix Biol. |volume=23 |issue= 7 |pages= 487–96 |year= 2005 |pmid= 15579315 |doi= 10.1016/j.matbio.2004.08.005 }}
- {{cite journal |vauthors=Scherberich A, Tucker RP, Degen M, etal |title=Tenascin-W is found in malignant mammary tumors, promotes alpha8 integrin-dependent motility and requires p38MAPK activity for BMP-2 and TNF-alpha induced expression in vitro. |journal=Oncogene |volume=24 |issue= 9 |pages= 1525–32 |year= 2005 |pmid= 15592496 |doi= 10.1038/sj.onc.1208342 }}
{{refend}}External links- ITGA8 Info with links in the Cell Migration Gateway
{{Integrins}}{{gene-10-stub}} 1 : Integrins |