| 词条 | Interleukin-10 receptor |
| 释义 |
| Name = interleukin 10 receptor, alpha | caption = | image = | width = | HGNCid = 5964 | Symbol = IL10RA | AltSymbols = IL10R | EntrezGene = 3587 | OMIM = 146933 | RefSeq = NM_001558 | UniProt = Q13651 | PDB = | ECnumber = | Chromosome = 11 | Arm = q | Band = 23 | LocusSupplementaryData = }}{{infobox protein | Name = interleukin 10 receptor, beta | caption = | image = | width = | HGNCid = 5965 | Symbol = IL10RB | AltSymbols = CRFB4, D21S58, D21S66 | EntrezGene = 3588 | OMIM = 123889 | RefSeq = NM_000628 | UniProt = Q08334 | PDB = | ECnumber = | Chromosome = 21 | Arm = q | Band = 22.1-22.2 | LocusSupplementaryData = }} Interleukin-10 receptor is a type II cytokine receptor. The receptor is tetrameric, composed of 2α[1] and 2β[2] subunits. The α subunit is expressed on haematopoietic cells (such as T, B, NK, mast, and dendritic cells) whilst the β subunit is expressed ubiquitously. References1. ^{{cite journal |vauthors=Liu Y, Wei SH, Ho AS, de Waal Malefyt R, Moore KW | title = Expression cloning and characterization of a human IL-10 receptor | journal = J. Immunol. | volume = 152 | issue = 4 | pages = 1821–9 | year = 1994 | pmid = 8120391 | doi = | url = http://www.jimmunol.org/cgi/content/abstract/152/4/1821 }} 2. ^{{cite journal |vauthors=Kotenko SV, Krause CD, Izotova LS, Pollack BP, Wu W, Pestka S | title = Identification and functional characterization of a second chain of the interleukin-10 receptor complex | journal = EMBO J. | volume = 16 | issue = 19 | pages = 5894–903 | year = 1997 | pmid = 9312047 | doi = 10.1093/emboj/16.19.5894| pmc = 1170220 }} External links
1 : Type II cytokine receptors |
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