| 词条 | Iodocholesterol |
| 释义 |
| Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 477209373 | IUPAC_name = (3S,8S,9S,10S,13R,14S,17R)-10-(iodomethyl)-13-methyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol | image = 19-Iodocholesterol.png | width = 250 | tradename = | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = | routes_of_administration = | bioavailability = | protein_bound = | metabolism = | elimination_half-life = | excretion = | CAS_number_Ref = | CAS_number = 37414-03-2 | CAS_supplemental = | class = | ATC_prefix = V09 | ATC_suffix = XA02 | ATC_supplemental = (131I) | PubChem = 3032874 | IUPHAR_ligand = | DrugBank_Ref = | DrugBank = | ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} | ChemSpiderID = 20086815 | UNII = 568E3L437Z | KEGG = | ChEBI = | ChEMBL = | C=27 | H=45 | I=1 | O=1 | molecular_weight = 510.561 g/mol | SMILES = CC(C)CCC[C@@H](C)[C@H]3CC[C@H]2[C@@H]4C\\C=C1\\C[C@@H](O)CC[C@]1(CI)[C@H]4CC[C@@]23C | StdInChI_Ref = {{stdinchicite|correct|chemspider}} | StdInChI = 1S/C27H45IO/c1-18(2)6-5-7-19(3)23-10-11-24-22-9-8-20-16-21(29)12-15-27(20,17-28)25(22)13-14-26(23,24)4/h8,18-19,21-25,29H,5-7,9-17H2,1-4H3/t19-,21+,22+,23-,24+,25+,26-,27-/m1/s1 | StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} | StdInChIKey = FIOAEFCJGZJUPW-FTLVODPJSA-N | synonyms = Iodocholesterol; 19-Iodocholesterol; Iodocholesterol (131I); 19-Iodocholest-5-en-3β-ol }}Iodocholesterol, or 19-iodocholesterol, also as iodocholesterol (131I) (INN), is a derivative of cholesterol with an iodine atom in the C19 position and a radiopharmaceutical.[1][2] When the iodine atom is a radioactive isotope (iodine-125 or iodine-131), it is used as an adrenal cortex radiocontrast agent in the diagnosis of patients suspected of having Cushing's syndrome, hyperaldosteronism, pheochromocytoma, and adrenal remnants following total adrenalectomy.[1][2] References1. ^1 {{cite book|author=J. Elks|title=The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies|url=https://books.google.com/books?id=0vXTBwAAQBAJ&pg=PA692|date=14 November 2014|publisher=Springer|isbn=978-1-4757-2085-3|pages=692–}} {{Radiopharmaceuticals}}{{drug-stub}}2. ^1 {{cite book|author1=Orlo H. Clark|author2=American Cancer Society|title=Endocrine Tumors|url=https://books.google.com/books?id=ZlqGWp3UZ6oC&pg=PA124|year=2003|publisher=PMPH-USA|isbn=978-1-55009-134-2|pages=124–}} 3 : Cholestanes|Organoiodides|Radiocontrast agents |
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