| 释义 |
- Function
- References
- Further reading
- External links
{{Infobox_gene}}Iroquois-class homeodomain protein IRX-5, also known as Iroquois homeobox protein 5, is a protein that in humans is encoded by the IRX5 gene.[1][2] Function IRX5 is a member of the Iroquois homeobox gene family. Members of this family appear to play multiple roles during pattern formation of vertebrate embryos.[1] References1. ^1 {{cite web | title = Entrez Gene: iroquois homeobox 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10265 | accessdate = }}
2. ^{{cite journal |vauthors=Ogura K, Matsumoto K, Kuroiwa A, Isobe T, Otoguro T, Jurecic V, Baldini A, Matsuda Y, Ogura T | title = Cloning and chromosome mapping of human and chicken Iroquois (IRX) genes | journal = Cytogenet. Cell Genet. | volume = 92 | issue = 3-4 | pages = 320–5 | year = 2001 | pmid = 11435706 | doi = 10.1159/000056921| url = | issn = }}
Further reading{{refbegin | 2}}- {{cite journal |vauthors=Lewis MT, Ross S, Strickland PA, etal |title=Regulated expression patterns of IRX-2, an Iroquois-class homeobox gene, in the human breast. |journal=Cell Tissue Res. |volume=296 |issue= 3 |pages= 549–54 |year= 1999 |pmid= 10370142 |doi= 10.1007/s004410051316}}
- {{cite journal |author=Bruneau BG |title=[Irx5: a transcription factor that regulates the cardiac repolarization gradient] |journal=Med Sci (Paris) |volume=22 |issue= 3 |pages= 231–2 |year= 2006 |pmid= 16527195 |doi= 10.1051/medsci/2006223231|url=http://www.erudit.org/fr/revues/ms/2006-v22-n3-ms1125/012768ar.pdf }}
- {{cite journal |vauthors=Myrthue A, Rademacher BL, Pittsenbarger J, etal |title=The iroquois homeobox gene 5 is regulated by 1,25-dihydroxyvitamin D3 in human prostate cancer and regulates apoptosis and the cell cycle in LNCaP prostate cancer cells. |journal=Clin. Cancer Res. |volume=14 |issue= 11 |pages= 3562–70 |year= 2008 |pmid= 18519790 |doi= 10.1158/1078-0432.CCR-07-4649 }}
- {{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2002 |pmid= 12477932 |doi= 10.1073/pnas.242603899 |pmc=139241}}
- {{cite journal |vauthors=Kanno S, Kuzuoka H, Sasao S, etal |title=A novel human AP endonuclease with conserved zinc-finger-like motifs involved in DNA strand break responses. |journal=EMBO J. |volume=26 |issue= 8 |pages= 2094–103 |year= 2007 |pmid= 17396150 |doi= 10.1038/sj.emboj.7601663 |pmc=1852789}}
{{refend}}External links- {{UCSC genome browser|IRX5}}
- {{UCSC gene details|IRX5}}
{{NLM content}}{{Transcription factors|g3}}{{gene-16-stub}} |