Isaac Webb may refer to:

• Ike Webb (1874–1950), English football goalkeeper
• Isaac Webb (shipbuilder) (1794–1840), American shipbuilder

• USS Izard
• USS Jacamar
• USS JACAMAR
• USS Jacamar (AMc-47)
• USS Jacamar (AMCU-25)
• USS Jacana
• USS Jacana (AMS-193)
• USS Jacana (MSC-193)
• USS Jaccard
• USS Jackamar (AMc-47)
• USS Jackdaw
• USS Jackdaw (AMS-21)
• USS Jackdaw (MSCO-21)
• USS Jackdaw (YMS-373)
• USS Jack Miller
• USS Jacob Bell
• USS Jacob Bell (1842)
• USS Jacob Jones (DE-130)
• USS Jaguar (IX-120)
• USS Jamaica (CVE-43)
• USS James C. Owens
• USS James E. Craig
• USS James E. Kyes
• USS James E. Kyes (DD-787)
• USS James E Williams