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词条 Iscotrizinol
释义

  1. References

{{chembox
| Verifiedfields = changed
| verifiedrevid = 443881587
| ImageFile = Iscotrizinol structure.svg
| ImageSize = 300px
| IUPACName = 4,4'-[[6-[[4-[[(1,1-dimethylethyl)amino]carbonyl]phenyl]amino]-1,3,5-triazine-2,4-diyl]diimino]bis-, bis(2-ethylhexyl)benzoate
| OtherNames = Diethylhexyl butamido triazone (INCI),
Uvasorb HEB (trade name)
|Section1={{Chembox Identifiers
| Abbreviations =
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
| ChemSpiderID = 7986571
| InChI1 = 1/C44H59N7O5/c1-8-12-14-30(10-3)28-55-39(53)33-18-24-36(25-19-33)46-42-48-41(45-35-22-16-32(17-23-35)38(52)51-44(5,6)7)49-43(50-42)47-37-26-20-34(21-27-37)40(54)56-29-31(11-4)15-13-9-2/h16-27,30-31H,8-15,28-29H2,1-7H3,(H,51,52)(H3,45,46,47,48,49,50)
| InChIKey1 = OSCJHTSDLYVCQC-UHFFFAOYAP
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| StdInChI = 1S/C44H59N7O5/c1-8-12-14-30(10-3)28-55-39(53)33-18-24-36(25-19-33)46-42-48-41(45-35-22-16-32(17-23-35)38(52)51-44(5,6)7)49-43(50-42)47-37-26-20-34(21-27-37)40(54)56-29-31(11-4)15-13-9-2/h16-27,30-31H,8-15,28-29H2,1-7H3,(H,51,52)(H3,45,46,47,48,49,50)
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
| StdInChIKey = OSCJHTSDLYVCQC-UHFFFAOYSA-N
| CASNo_Ref = {{cascite|correct|??}}
| CASNo = 154702-15-5
| EINECS =
| PubChem = 9810816
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = 2UTZ0QC864
| SMILES = O=C(OCC(CC)CCCC)c1ccc(cc1)Nc2nc(nc(n2)Nc3ccc(C(=O)OCC(CC)CCCC)cc3)Nc4ccc(C(=O)NC(C)(C)C)cc4
| InChI = 1/C44H59N7O5/c1-8-12-14-30(10-3)28-55-39(53)33-18-24-36(25-19-33)46-42-48-41(45-35-22-16-32(17-23-35)38(52)51-44(5,6)7)49-43(50-42)47-37-26-20-34(21-27-37)40(54)56-29-31(11-4)15-13-9-2/h16-27,30-31H,8-15,28-29H2,1-7H3,(H,51,52)(H3,45,46,47,48,49,50)/f/h45-47,51H
| RTECS =
| MeSHName =
| ChEBI_Ref = {{ebicite|correct|EBI}}
| ChEBI =
| KEGG_Ref = {{keggcite|changed|kegg}}
| KEGG = D09714
}}
|Section2={{Chembox Properties
| C=44 | H=59 | N=7 | O=5
| MolarMass = 765.981
| Appearance =
| Density =
| MeltingPt =
| MeltingPt_notes =
| BoilingPt =
| BoilingPt_notes =
| Solubility =
| SolubleOther =
| Solvent =
| pKa =
| pKb = }}
|Section7={{Chembox Hazards
| ExternalSDS =
| EUClass =
| MainHazards =
| NFPA-H =
| NFPA-F =
| NFPA-R =
| NFPA-S =
| RPhrases =
| SPhrases =
| RSPhrases =
| FlashPt =
| AutoignitionPt =
| ExploLimits =
| PEL = }}
}}

Iscotrizinol (USAN,[1] INCI diethylhexyl butamido triazone) is an organic compound used in sunscreens to absorb UVB and some UVA radiation [2] with a peak protection at 310nm.[3] It is one of the most photostable chemical sunscreens known today with 25 hours required to lose 10% of its SPF protection ability.[4] It is marketed as Uvasorb HEB by 3V Sigma.

References

1. ^[https://searchusan.ama-assn.org/undefined/documentDownload?uri=%2Funstructured%2Fbinary%2Fusan%2Fiscotrizinol.pdf Statement on a nonproprietary name adopted by the USAN Council]
2. ^incidecoder.com: Diethylhexyl Butamido Triazone
3. ^{{cite journal| title = Study of the efficacy of 18 sun filters authorized in European Union tested in vitro.| date = June 2007| vauthors = Couteau C, Pommier M, Paparis E, Coiffard LJ| journal = Pharmazie| volume=62 | pages=449-452| pmid = 17663193| doi = 10.1691/ph.2007.6.6247}}
4. ^{{cite journal| title = Study of the photostability of 18 sunscreens in creams by measuring the SPF in vitro| date = May 2007| vauthors = Couteau C, Faure A, Fortin J, Paparis E, Coiffard LJ| journal = Journal of Pharmaceutical and Biomedical Analysis| volume=44 | pages= 270-273| doi = 10.1016/j.jpba.2007.01.052}}
{{Sunscreening agents}}{{amine-stub}}

7 : Sunscreening agents|Triazines|Aromatic amines|Benzoates|Benzamides|Anilines|Tert-butyl compounds

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