词条 | Isometamidium chloride |
释义 |
| IUPAC_name = 3-[N'-[(3-amino-5-ethyl-6-phenyl-8-phenanthridin-5-iumyl)imino]hydrazino]benzamidine chloride | image = Isometamidium chloride.png | tradename = | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = | routes_of_administration = | bioavailability = | protein_bound = | metabolism = | elimination_half-life = | excretion = | CAS_number = 34301-55-8 | ATCvet = yes | ATC_prefix = P51 | ATC_suffix = AX19 | PubChem = 92295 | DrugBank = | ChemSpiderID = 83326 | UNII_Ref = {{fdacite|correct|FDA}} | UNII = 7NH28I651F | chemical_formula = | C=28 | H=26 | Cl=1 | N=7 | molecular_weight = 496.01 g/mol | smiles = [Cl-].[N@H]=C(N)c1cc(ccc1)N/N=N/c4ccc3c2ccc(N)cc2[n+](c(c3c4)c5ccccc5)CC | StdInChI = 1S/C28H25N7.ClH/c1-2-35-26-16-20(29)11-13-24(26)23-14-12-22(17-25(23)27(35)18-7-4-3-5-8-18)33-34-32-21-10-6-9-19(15-21)28(30)31;/h3-17,29H,2H2,1H3,(H4,30,31,32,33);1H | StdInChIKey = QNZJTSGALAVCLH-UHFFFAOYSA-N }}Isometamidium chloride is a trypanocidal agent used in veterinary medicine.[1][2] References1. ^{{cite journal |title = Isometamidium chloride prophylaxis against Trypanosoma congolense challenge and the development of immune responses in Boran cattle |author1=D. D. Whitelaw |author2=I. R. Bell |author3=P. H. Holmes |author4=S. K. Moloo |author5=H. Hirumi |author6=G. M. Urquhart |author7=M. Murray |journal = Veterinary Record |year = 1986 |volume = 118 |pages = 722–726 | doi = 10.1136/vr.118.26.722}} {{antiinfective-drug-stub}}2. ^{{cite journal |title= Factors influencing the duration of isometamidiumchloride (samorin) prophylaxis against experimental challenge with metacyclic forms of Trypanosoma congolense |author1=A. S. Peregrine |author2=O. Ogunyemi |author3=D. D. Whitelaw |author4=P. H. Holmes |author5=S. K. Moloo |author6=H. Hirumi |author7=G. M. Urquhart |author8=M. Murray |journal = Veterinary Parasitology |volume = 28 |issue = 1–2 |date=April 1988 |pages = 53–64 |doi=10.1016/0304-4017(88)90018-0}} 3 : Amidines|Antiparasitic agents|Quaternary ammonium compounds |
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