“Isonocardicin synthase”的意思、由来-开放百科全书

词条

Isonocardicin synthase

释义

References

{{enzyme
| Name = isonocardicin synthase
| EC_number = 2.5.1.38
| CAS_number = 118246-74-5
| IUBMB_EC_number = 2/5/1/38
| GO_code = 0050007
| image =
| width =
| caption =
}}

In enzymology, an isonocardicin synthase ({{EC number|2.5.1.38}}) is an enzyme that catalyzes the chemical reaction

S-adenosyl-L-methionine + nocardicin E 5'-methylthioadenosine + isonocardicin A

Thus, the two substrates of this enzyme are S-adenosyl-L-methionine and nocardicin E, whereas its two products are 5'-methylthioadenosine and isonocardicin A.

This enzyme belongs to the family of transferases, specifically those transferring aryl or alkyl groups other than methyl groups. The systematic name of this enzyme class is S-adenosyl-L-methionine:nocardicin-E 3-amino-3-carboxypropyltransferase. This enzyme is also called nocardicin aminocarboxypropyltransferase.

References

{{cite journal| date = 1988 | title = Cell-free biosynthesis of nocardicin A from nocardicin E and S-adenosylmethionine | journal = J. Am. Chem. Soc. | volume = 110 | pages = 8238–8239 | doi = 10.1021/ja00232a047 |first1 = Brenda A. |last1 = Wilson | last2 = Bantia | first2 = Shanta. | last3 = Salituro | first3 = Gino M. | last4 = Reeve | first4 = Anne M. | last5 = Townsend | first5 = Craig A. | issue = 24 }}

2 : EC 2.5.1|Enzymes of unknown structure

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