James Gamble may refer to:

• James Gamble (industrialist) (1803–1891), U.S.-based Irish soapmaker and industrialist; co-founder of Procter & Gamble Company
• James Gamble (congressman) (1809–1883), U.S. Representative from Pennsylvania
• James Gamble (telegraph) (18??- ?)
• James Sykes Gamble (1847–1925), English botanist
• James Fulton Gamble, Northern Irish politician

• Jack Coles
• Jack Coles (musician)
• Jack Collins (1930s footballer)
• Jack Collins (New Jersey)
• Jack Colreavy
• Jack Colwell
• Jack Compton Gannon
• Jack Condy
• Jack Conklin
• Jack Connally
• Jack Connell
• Jack Connell (footballer)
• Jack Conner (footballer, born 1891)
• Jack Cooper (English musician)
• Jack Cooper (musician)
• Jack Copeland (surgeon)
• Jack Corgan
• Jack Cosgrove (rugby)
• Jack Cosgrove (rugby union)
• Jack County Courthouse
• Jack Courtney
• Jack Courtney (disambiguation)
• Jack Coventry
• Jack Cowell
• Jack Coxon