José Machado may refer to:

• José Machado (rower) (born 1928), Portuguese Olympic rower
• José Ramón Machado Ventura (born 1930), vice-president of Cuba (2008 to date)
• José Machado (São Tomé and Príncipe), Portuguese governor of São Tomé and Príncipe (1955–56)
• José Manuel Machado (1756–1852), Spanish soldier, ranchero, early citizen of the pueblo of San Diego

• U.S. Office of Public Diplomacy for Latin America and the Caribbean
• U.S. Office of Special Counsel
• U.S. Office of the Trade Representative
• US official number
• U.S. official state dogs
• Usogorsk
• Usogorsk Urban Settlement
• Usogui
• USO Haifa
• Usoi language
• USO Israel
• U.S. Olginatese
• Usolskaya
• Usolskoye
• Usolskoye Urban Settlement
• Usolye-Sibirskoye Urban Okrug
• U.S. Olympian
• US Olympic Festival
• U.S. Olympic Festival
• US Olympic flag bearers
• U.S. Olympic flag bearers
• US Olympic TEAM TRIALS
• US Olympic Track and Field Trials
• US - Oman relations
• U.S.-Oman relations