| 释义 |
- References
- Further reading
{{Infobox_gene}}Katanin p60 ATPase-containing subunit A1 is an enzyme that in humans is encoded by the KATNA1 gene.[1][2]{{PBB_Summary
| section_title =
| summary_text = Microtubules, polymers of alpha and beta tubulin subunits, form the mitotic spindle of a dividing cell and help to organize membranous organelles during interphase. Katanin is a heterodimer that consists of a 60 kDa ATPase (p60 subunit A 1) and an 80 kDa accessory protein (p80 subunit B 1). The p60 subunit acts to sever and disassemble microtubules, while the p80 subunit targets the enzyme to the centrosome. This gene encodes the p80 subunit. This protein is a member of the AAA family of ATPases.[3]
}}References1. ^{{cite journal |vauthors=McNally FJ, Thomas S | title = Katanin is responsible for the M-phase microtubule-severing activity in Xenopus eggs | journal = Mol Biol Cell | volume = 9 | issue = 7 | pages = 1847–61 |date=Jan 1999 | pmid = 9658175 | pmc = 25426 | doi = 10.1091/mbc.9.7.1847}}
2. ^{{cite web | title = Entrez Gene: KATNA1 katanin p60 (ATPase-containing) subunit A 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=11104| accessdate = }}
3. ^{{cite web | title = Entrez Gene: KATNA1 katanin p60 (ATPase-containing) subunit A 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=11104| accessdate = }}
Further reading{{refbegin | 2}}- {{cite journal |vauthors=McNally FJ, Vale RD |title=Identification of katanin, an ATPase that severs and disassembles stable microtubules. |journal=Cell |volume=75 |issue= 3 |pages= 419–29 |year= 1993 |pmid= 8221885 |doi=10.1016/0092-8674(93)90377-3 }}
- {{cite journal |vauthors=McNally FJ, Okawa K, Iwamatsu A, Vale RD |title=Katanin, the microtubule-severing ATPase, is concentrated at centrosomes. |journal=J. Cell Sci. |volume=109 |issue= 3|pages= 561–7 |year= 1997 |pmid= 8907702 |doi= }}
- {{cite journal |vauthors=Hartman JJ, Mahr J, McNally K, etal |title=Katanin, a microtubule-severing protein, is a novel AAA ATPase that targets to the centrosome using a WD40-containing subunit. |journal=Cell |volume=93 |issue= 2 |pages= 277–87 |year= 1998 |pmid= 9568719 |doi=10.1016/S0092-8674(00)81578-0 }}
- {{cite journal |vauthors=Ahmad FJ, Yu W, McNally FJ, Baas PW |title=An essential role for katanin in severing microtubules in the neuron. |journal=J. Cell Biol. |volume=145 |issue= 2 |pages= 305–15 |year= 1999 |pmid= 10209026 |doi=10.1083/jcb.145.2.305 | pmc=2133110 }}
- {{cite journal |vauthors=Syu LJ, Saltiel AR |title=Lipotransin: a novel docking protein for hormone-sensitive lipase. |journal=Mol. Cell |volume=4 |issue= 1 |pages= 109–15 |year= 1999 |pmid= 10445032 |doi=10.1016/S1097-2765(00)80192-6 }}
- {{cite journal |vauthors=McNally KP, Bazirgan OA, McNally FJ |title=Two domains of p80 katanin regulate microtubule severing and spindle pole targeting by p60 katanin. |journal=J. Cell Sci. |volume=113 |issue= 9|pages= 1623–33 |year= 2000 |pmid= 10751153 |doi= }}
- {{cite journal |vauthors=Buster D, McNally K, McNally FJ |title=Katanin inhibition prevents the redistribution of gamma-tubulin at mitosis. |journal=J. Cell Sci. |volume=115 |issue= Pt 5 |pages= 1083–92 |year= 2002 |pmid= 11870226 |doi= }}
- {{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 }}
- {{cite journal |vauthors=Mungall AJ, Palmer SA, Sims SK, etal |title=The DNA sequence and analysis of human chromosome 6. |journal=Nature |volume=425 |issue= 6960 |pages= 805–11 |year= 2003 |pmid= 14574404 |doi= 10.1038/nature02055 }}
- {{cite journal |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
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