| 释义 |
- See also
- References
- Further reading
- External links
{{Infobox_gene}}Potassium inwardly-rectifying channel, subfamily J, member 14 (KCNJ14), also known as Kir2.4, is a human gene.[1]{{PBB_Summary
| section_title =
| summary_text = Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel, and probably has a role in controlling the excitability of motor neurons. Two transcript variants encoding the same protein have been found for this gene.[1]
}}See also- Inward-rectifier potassium ion channel
References1. ^1 {{cite web | title = Entrez Gene: KCNJ14 potassium inwardly-rectifying channel, subfamily J, member 14| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3770| accessdate = }}
Further reading{{refbegin | 2}}- {{cite journal |vauthors=Kubo Y, Adelman JP, Clapham DE, etal |title=International Union of Pharmacology. LIV. Nomenclature and molecular relationships of inwardly rectifying potassium channels |journal=Pharmacol. Rev. |volume=57 |issue= 4 |pages= 509–26 |year= 2006 |pmid= 16382105 |doi= 10.1124/pr.57.4.11 }}
- {{cite journal |vauthors=Bonaldo MF, Lennon G, Soares MB |title=Normalization and subtraction: two approaches to facilitate gene discovery |journal=Genome Res. |volume=6 |issue= 9 |pages= 791–806 |year= 1997 |pmid= 8889548 |doi=10.1101/gr.6.9.791 }}
- {{cite journal |vauthors=Töpert C, Döring F, Wischmeyer E, etal |title=Kir2.4: a novel K+ inward rectifier channel associated with motoneurons of cranial nerve nuclei |journal=J. Neurosci. |volume=18 |issue= 11 |pages= 4096–105 |year= 1998 |pmid= 9592090 |doi= 10.1523/JNEUROSCI.18-11-04096.1998}}
- {{cite journal |vauthors=Töpert C, Döring F, Derst C, etal |title=Cloning, structure and assignment to chromosome 19q13 of the human Kir2.4 inwardly rectifying potassium channel gene (KCNJ14) |journal=Mamm. Genome |volume=11 |issue= 3 |pages= 247–9 |year= 2000 |pmid= 10723734 |doi=10.1007/s003350010047 |hdl=11858/00-001M-0000-0012-F99D-B }}
- {{cite journal |vauthors=Hughes BA, Kumar G, Yuan Y, etal |title=Cloning and functional expression of human retinal kir2.4, a pH-sensitive inwardly rectifying K(+) channel |journal=Am. J. Physiol., Cell Physiol. |volume=279 |issue= 3 |pages= C771–84 |year= 2000 |pmid= 10942728 |doi= 10.1152/ajpcell.2000.279.3.C771}}
- {{cite journal |vauthors=Nagase T, Kikuno R, Ohara O |title=Prediction of the coding sequences of unidentified human genes. XXII. The complete sequences of 50 new cDNA clones which code for large proteins |journal=DNA Res. |volume=8 |issue= 6 |pages= 319–27 |year= 2002 |pmid= 11853319 |doi=10.1093/dnares/8.6.319 }}
- {{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 }}
- {{cite journal |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
- {{cite journal |vauthors=Fang Y, Schram G, Romanenko VG, etal |title=Functional expression of Kir2.x in human aortic endothelial cells: the dominant role of Kir2.2 |journal=Am. J. Physiol., Cell Physiol. |volume=289 |issue= 5 |pages= C1134–44 |year= 2005 |pmid= 15958527 |doi= 10.1152/ajpcell.00077.2005 }}
- {{cite journal |vauthors=Tennant BP, Cui Y, Tinker A, Clapp LH |title=Functional expression of inward rectifier potassium channels in cultured human pulmonary smooth muscle cells: evidence for a major role of Kir2.4 subunits |journal=J. Membr. Biol. |volume=213 |issue= 1 |pages= 19–29 |year= 2007 |pmid= 17347781 |doi= 10.1007/s00232-006-0037-y | pmc=1973150 }}
{{refend}} External links - {{MeshName|KCNJ14+protein,+human}}
{{NLM content}}{{Ion channels|g3}}{{membrane-protein-stub}} 1 : Ion channels |