| 词条 | Kenneth B. Storey |
| 释义 |
|name = Kenneth Storey |image = Kenneth Storey in his lab.jpg |caption = |birth_name = Kenneth Bruce Storey |birth_date = {{birth date and age|1949|10|23}} |birth_place = Taber, Alberta, Canada |death_date = |death_place = |residence = Ottawa, Ontario, Canada |citizenship = Canadian |nationality = |ethnicity = |fields = Molecular Physiology Biochemistry Biochemical Adaptation |workplaces = Carleton University, Canada |alma_mater = |doctoral_advisor = Peter Hochachka |academic_advisors = |notable_students = [https://www.kenstoreylab.com/people/current-students/ Current Students] [https://www.kenstoreylab.com/people/past-3-0-2/ Past Students] |known_for = |author_abbrev_bot = |author_abbrev_zoo = |influences = |influenced = |awards = Royal Society of Canada Fellow {{small|(1990)}} Flavelle Medal {{small|(2010)}} [https://www.csz-scz.ca/awards/fej-fry Fry Medal] {{small|(2011)}} [https://www.societyforcryobiology.org/fellows Cryo-Fellow] {{small|(2012)}} |religion = |signature = |footnotes = }}Kenneth B. Storey, Ph.D. {{post-nominals|country=CAN|FRSC}} (born October 23, 1949) is a Canadian scientist whose work draws from a variety of fields including biochemistry and molecular biology. He is a Professor of Biology, Biochemistry and Chemistry at Carleton University in Ottawa, Canada. Storey has a world-wide reputation for his research on biochemical adaptation - the molecular mechanisms that allow animals to adapt to and endure severe environmental stresses such as deep cold, oxygen deprivation, and desiccation.[1] BiographyKenneth Storey studied biochemistry at the University of Calgary (B.Sc. '71) and zoology at the University of British Columbia (Ph.D. '74).[2][3] Storey is a Professor of Biochemistry, cross-appointed in the Departments of Biology, Chemistry and Neuroscience and holds the Canada Research Chair in Molecular Physiology at Carleton University in Ottawa, Canada.[4] Storey is an elected fellow of the Royal Society of Canada,[5] of the Society for Cryobiology[6] and of the American Association for the Advancement of Science. He has won fellowships and awards for research excellence including the Fry medal from the Canadian Society of Zoologists (2011), the Flavelle medal from the Royal Society of Canada (2010), Ottawa Life Sciences Council Basic Research Award (1998), a [https://killamprogram.canadacouncil.ca/ Killam Senior Research Fellowship] (1993–1995), the Ayerst Award from the [https://csmb-scbm.ca/ Canadian Society for Molecular Biosciences] (1989), an E.W.R. Steacie Memorial Fellowship from the Natural Sciences and Engineering Research Council of Canada (1984–1986), and four Carleton University Research Achievement Awards. Storey is the author of over 844 research articles, the editor of seven books, has given over 500 talks at conferences and institutes worldwide, and organized numerous international symposia.[7] ResearchStorey is one of the most cited researchers in the world.[8] Storey's research includes studies of enzyme properties, gene expression, protein phosphorylation, and cellular signal transduction mechanisms to seek out the basic principles of how organisms endure and flourish under extreme conditions. He is particularly known within the field of cryobiology for his studies of animals that can survive freezing, especially the frozen "frog-sicles" (Rana sylvatica) that have made his work popular with multiple TV shows and magazines.[9][10][11] Storey's studies of the adaptations that allow frogs, insects, and other animals to survive freezing have made major advances in the understanding of how cells, tissues and organs can endure freezing.[11] Storey was also responsible for the discovery that some turtle species are freeze tolerant: newly hatched painted turtles that spend their first winter on land (Chrysemys picta marginata & C. p. bellii). These turtles are unique as they are the only reptiles, and highest vertebrate life form, known to tolerate prolonged natural freezing of extracellular body fluids during winter hibernation.[12] These advances may aid the development of organ cryopreservation technology.[4] A second area of his research is metabolic rate depression - understanding the mechanisms by which some animals can sharply reduce their metabolism and enter a state of hypometabolism or torpor that allows them to survive over the long term under difficult environmental stresses. His studies have identified molecular mechanisms that underlie metabolic arrest across phylogeny and that support phenomena including mammalian hibernation, estivation, and anoxia and ischemia tolerance. Control mechanisms include transcription factor changes that alter gene expression, and reversible phosphorylation of key metabolic enzymes by protein kinases and protein phosphatases. These studies across multiple species also hold key applications for medical science, particularly for preservation technologies that aim to extend the survival time of excised organs in cold or frozen storage.[4] Additional applications include insights into hyperglycemia in metabolic syndrome and diabetes,[13] and anoxic and ischemic damage caused by heart attack and stroke.[14] Furthermore, Storey's lab has created several web based programs freely available for [https://www.kenstoreylab.com/research-tools/ data management, data plotting, and micro RNA analysis]. Website[https://www.kenstoreylab.com/ Main Page] [https://www.kenstoreylab.com/ken-storey/ Personal Profile] Selected recent publicationsFull list on [https://scholar.google.ca/citations?sortby=pubdate&hl=en&user=mzhKxEoAAAAJ&view_op=list_works Google Scholar] Full list on [https://www.ncbi.nlm.nih.gov/pubmed/?term=Storey+KB PubMed] Books
|editor1-last=Storey |editor1-first=K.B. |editor2-last=Tanino |editor2-first=K.K. |year=2012 |title=Temperature Adaptation in a Changing Climate |publisher=CABI Publishers |location=Walllingford |url=http://bookshop.cabi.org/?page=2633&pid=2387&site=191}}
|last=Storey |first=K.B. |year=2004 |title=Functional Metabolism: Regulation and Adaptation |publisher=Wiley-Liss |location=Hoboken, NJ |url=http://ca.wiley.com/WileyCDA/WileyTitle/productCd-047141090X.html }} Selected Review Articles
Boards
Professional Positions
Professional Honours[https://www.kenstoreylab.com/ken-storey/ List of Honours] Recent Research Activities[https://www.kenstoreylab.com/ken-storey/ List of Research Activities] References1. ^{{cite web|url=https://www.pbs.org/safarchive/3_ask/archive/bio/74_kstorey_bio.html|title=Kenneth Storey Bio|work=Ask the Scientists|publisher=PBS}} {{Authority control}}{{DEFAULTSORT:Storey, Kenneth B.}}2. ^{{Cite web | url=http://kenstoreylab.com/?page_id=4 | title=Ken Storey | the Storey Lab: Cell and Molecular Responses to Stress}} 3. ^{{Cite web | url=https://www.researchgate.net/profile/Kenneth_Storey/info | title=Kenneth B. Storey | Ph.D., Professor & Canada Research Chair | Carleton University, Ottawa | Institute of Biochemistry}} 4. ^1 2 3 {{cite web |url=http://research.carleton.ca/docs/chairs/storey.pdf |title=How research in Ottawa can preserve organs for transplant in the future |publisher=Carleton University }}{{dead link|date=May 2017 |bot=InternetArchiveBot |fix-attempted=yes }} 5. ^{{cite web |url=http://research.carleton.ca/royal.php |title=Royal Society of Canada members at Carleton University |publisher=Carleton University |deadurl=yes |archiveurl=https://web.archive.org/web/20090829182904/http://research.carleton.ca/royal.php |archivedate=2009-08-29 |df= }} 6. ^{{cite web|url=http://www.societyforcryobiology.org |title=Society for Cryobiology}} 7. ^{{cite web|url=http://http-server.carleton.ca/~kbstorey/|title=STOREY Lab}} 8. ^{{Cite web | url=https://www.researchgate.net/profile/Kenneth_Storey | title=Kenneth B. Storey | Ph.D., Professor & Canada Research Chair | Carleton University, Ottawa | Institute of Biochemistry}} 9. ^{{cite news |url=http://www.globecampus.ca/blogs/research-matters/tags/thaw/ |title=Frozen frogs thaw out and hop away |last=McIlroy |first=Anne |date=3 December 2009 |work=The Globe and Mail |accessdate=15 January 2010 |deadurl=yes |archiveurl=https://web.archive.org/web/20100822043143/http://www.globecampus.ca/blogs/research-matters/tags/thaw/ |archivedate=22 August 2010 |df= }} 10. ^{{cite web|url=http://watch.discoverychannel.ca/clip2585#clip2585|title=Melted Frogsicle|publisher=Discovery Channel|format=Silverlight video}} 11. ^1 {{cite web|url=http://watch.discoverychannel.ca/clip7808#clip7808|title=Freeze and thaw frogs|publisher=Discovery Channel|format=Silverlight video}} 12. ^{{cite journal|pmc=282428|title=Hatchling turtles survive freezing during winter hibernation|year=1988|volume=85|issue=21|pmid=3186730|last1=Storey|first1=KB|last2=Storey|first2=JM|last3=Brooks|first3=SP|last4=Churchill|first4=TA|last5=Brooks|first5=RJ|pages=8350–4|journal=Proceedings of the National Academy of Sciences of the United States of America|doi=10.1073/pnas.85.21.8350}} 13. ^{{Cite web | url=http://sandrablakeslee.com/articles/ice_age_diabetes_may05.php | title=New Theory Places Origin of Diabetes in an Age of Icy Hardships | Ice Age DiabetesS}} 14. ^{{Cite web |url=http://health.usnews.com/usnews/health/articles/050523/23hibernate.htm# |title=Archived copy |access-date=2010-01-21 |archive-url=https://web.archive.org/web/20081030064650/http://health.usnews.com/usnews/health/articles/050523/23hibernate.htm# |archive-date=2008-10-30 |dead-url=yes |df= }} 10 : 1949 births|Canada Research Chairs|Carleton University|Carleton University faculty|Cryobiology|Fellows of the Royal Society of Canada|Living people|Molecular biology|People from Taber, Alberta|University of Calgary alumni |
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