词条 | Kimberly Bergalis |
释义 |
|name = Kimberly Bergalis |image = |caption = |birth_name = Kimberly Ann Bergalis |birth_date = {{Birth date|1968|1|19}} |birth_place = Tamaqua, Pennsylvania, U.S. |death_date = {{Death date and age|1991|12|8|1968|1|19}} |death_place = Fort Pierce, Florida, U.S. |death_cause = AIDS-related complications |resting_place = Saints Peter and Paul RC Lithuanian Cemetery |alma_mater = University of Florida |known_for = First known case of clinically-transmitted HIV |occupation = |nationality = American }} Kimberly Ann Bergalis (January 19, 1968 – December 8, 1991) was an American woman who was one of six patients purportedly infected with HIV by dentist David J. Acer, who was infected with HIV and died of AIDS in September 1990.[1] This incident is the first known case of clinical transmission of HIV. BackgroundThe eldest of three daughters, Bergalis was born in Tamaqua, Pennsylvania in 1968, where her family lived until moving to Florida in 1978. In 1985, she enrolled at the University of Florida and majored in business. In December 1987, dentist Dr. David Acer removed two of Bergalis's molars. Acer was HIV-positive at the time, having been diagnosed that fall. In March 1989 Bergalis began to show symptoms of AIDS and was diagnosed with the disease in January 1990.[2] The Centers for Disease Control and Prevention (CDC) initial report[3] that she had likely acquired her infection from her dentist prompted Acer to write an open letter requesting that his patients be tested for HIV infection. The Florida Department of Health and Rehabilitative Services tested over 1000 patients, discovering two additional HIV-positive patients.[4] The CDC would eventually identify a total of ten HIV-positive former Acer patients, and link the infections of six to their dentist.[5] CDC investigationThe CDC conducted a phylogenetic analysis of the DNA sequences of the viral envelope gene. The analysis revealed that the viral sequences from five patients, including Bergalis, were more closely related to the dentist's viral sequences than to those from local controls.[6] Later analyses identified another HIV-positive patient with a viral sequence closely related to Acer's.[7][8] Independent review of the CDC tests strengthened the case that Bergalis' HIV infection was linked to Acer.[5] The time between Bergalis' dental procedure and the development of AIDS (24 months)[9] was short; 1% of infected homosexual/bisexual men[10] and 5% of infected transfusion recipients[11] develop AIDS within two years of infection. Political reactionDuring the last months of her life, Bergalis' case was cited by some politicians and journalists as an example of a 'blameless' HIV infection that had been allowed to happen due to the CDC and the healthcare industry being overly responsive to the concerns of AIDS activists and the gay community. In an obituary, the National Review wrote that Bergalis ...came to feel she had a special calling...to bring a glimmer of truth, however forlorn, into a debate characterized by confusion, denial, smugness, and suicidal self-indulgence... 'No sexual history' is how the jaded describe a chaste woman of 23 who, as Miss Bergalis explained to disbelieving interviewers, 'wanted to wait for marriage.' Marriage and its joys will never come for Kimberly Bergalis, but in her integrity and courage she affirmed that other things were also precious.[12] Death and posthumous controversyOn December 8, 1991, Bergalis died of AIDS-related complications at her home in Fort Pierce, Florida.[1] Her funeral was held on December 12 in her hometown of Tamaqua, Pennsylvania after which she was buried in Saints Peter and Paul RC Lithuanian Cemetery.[14] Shortly after Bergalis’ death, a small park on Hutchinson Island South, Florida was renamed Kimberly Bergalis Memorial Park in her memory.[15] Nearly three years after Bergalis’ death, in June 1994, CBS aired an episode of 60 Minutes that included a segment covering Dr. Acer and the patients he infected. The episode alleged that Bergalis, who said she was a virgin, had been treated for genital warts, a sexually transmitted disease, and showed her on videotape allegedly claiming to have had sex with two different men during her life. However, none of Bergalis' former serious boyfriends tested positive for HIV. In addition, the 60 Minutes anchors argued that the CDC may have botched the genetic tests that proved that Bergalis had the same strain of HIV as her dentist. The television broadcast was dismissed by CDC scientists as misleading and inaccurate.[16] Stephen Barr, a journalist who contributed to the show, rebutted this dismissal.[17][18]{{dubious|Questionable citations|date=June 2014}} References1. ^1 Lambert, Bruce (December 9, 1991). [https://www.nytimes.com/1991/12/09/obituaries/kimberly-bergalis-is-dead-at-23-symbol-of-debate-over-aids-tests.html Kimberly Bergalis Is Dead at 23; Symbol of Debate Over AIDS Tests.] New York Times 2. ^{{cite news|url=http://www.people.com/people/archive/article/0,,20113381,00.html|title=A Life Stolen Early |last=Johnson|first=Bonnie|date=1990-10-22|publisher=People|accessdate=2008-12-24}} 3. ^{{Cite journal | author = CDC | journal = Morb. Mortal. Wkly. Rep. |title=Update: transmission of HIV infection during invasive dental procedures | volume = 39 | pages = 489 | year = 1990 | url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1488431/}} 4. ^{{Cite news | url = https://www.nytimes.com/1990/09/22/us/2-new-aids-infections-deepen-florida-mystery.html | title = 2 New AIDS Infections Deepen Florida Mystery | date = 1990-09-22 | publisher =The New York Times| accessdate = 2010-12-13}} 5. ^1 Hillis DM, Huelsenbeck JP (1994). Nature 369:24-5 6. ^{{Cite journal | last = Ou | first = Chin-Yih | title = Molecular epidemiology of HIV transmission in a dental practice | journal = Science | volume = 256 | pages = 1165–1171 | year = 1992 | jstor = 2877255|doi = 10.1126/science.256.5060.1165 | issue = 5060 | pmid = 1589796 |display-authors=etal}} 7. ^{{cite web|url=https://www.cdc.gov/mmwr/preview/mmwrhtml/00001877.htm|title=Epidemiologic Notes and Reports Update: Transmission of HIV Infection during an Invasive Dental Procedure -- Florida |accessdate=2007-02-28|author=CDC|authorlink= Centers for Disease Control and Prevention|date=1991-01-18 }} 8. ^{{cite web|url=https://www.cdc.gov/mmwr/preview/mmwrhtml/00014428.htm|title=Epidemiologic Notes and Reports Update: Transmission of HIV Infection During Invasive Dental Procedures --- Florida |accessdate=2007-02-28|author=CDC|authorlink= Centers for Disease Control and Prevention|date=1991-06-14 }} 9. ^{{cite web|url=https://www.cdc.gov/mmwr/preview/mmwrhtml/00001679.htm|title=Possible Transmission of Human Immunodeficiency Virus to a Patient during an Invasive Dental Procedure |accessdate=2007-02-28|author=CDC|authorlink= Centers for Disease Control and Prevention|date=1990-07-27 }} 10. ^{{Cite conference| first = A.R.| last = Lifson|author2=Hessol N., Rutherford G.| title = Natural history of HIV infection in a cohort of homosexual and bisexual men: clinical and immunologic outcome| booktitle = Vol. 1 VI International Conference on AIDS| pages = 142| date = June 20–24, 1990|location = San Francisco |display-authors=etal}} 11. ^{{Cite journal| last = Ward| first = J.R.|author2=Bush T.J., Perkins, H.A.| title = The natural history of transfusion-associated infection with human immunodeficiency virus: factors influencing the rate of progression to disease| journal = N Engl J Med| volume = 321| pages = 947–52|doi = 10.1056/NEJM198910053211406| pmid = 2779617| year = 1989| issue = 14|display-authors=etal}} 12. ^Editorial staff (December 30, 1991). Kimberly Bergalis, R I P National Review 13. ^Hilts, Philip J. [https://www.nytimes.com/1991/09/27/us/aids-patient-urges-congress-to-pass-testing-bill.html], The New York Times, September 27, 1991, accessed December 13, 2010. 14. ^{{cite web|last1=Todd|first1=Susan|title=Hundreds Mourn Bergalis|url=http://articles.mcall.com/1991-12-13/news/2822327_1_kimberly-bergalis-hiv-policy-immune-deficiency-syndrome|website=The Morning Call|publisher=mcall.com|accessdate=May 27, 2018|date=December 13, 1991}} 15. ^{{cite book|last1=Wilson|first1=Jean Ellen|title=Legendary Locals of Fort Pierce|date=2014|publisher=Arcadia Publishing|isbn=1-467-10127-3|page=124}} 16. ^{{cite journal | first = C. A. | last = Ciesielski | journal = Ann Intern Med | title = The 1990 Florida dental investigation, The press and the science | volume = 121 | pages = 886–88 | pmid = 7978703 | year = 1994 | issue = 11 | doi=10.7326/0003-4819-121-11-199412010-00011|display-authors=etal}} 17. ^{{cite journal|last =Barr|first=Stephen|date=1996-01-15|title = The 1990 Florida Dental Investigation: Is the Case Really Closed?|journal = Annals of Internal Medicine| volume = 124| issue = 2| pages = 250–254| issn = 0003-4819| url = http://www.annals.org/cgi/content/full/124/2/250| accessdate = 2007-02-28| pmid = 8534001| doi=10.7326/0003-4819-124-2-199601150-00009}} 18. ^{{cite journal| last = Brown| first = David| date = 1996-01-15| title = The 1990 Florida Dental Investigation: Theory and Fact| journal = Annals of Internal Medicine| volume = 124| issue = 2| pages = 255–256| issn = 0003-4819| url = http://www.annals.org/cgi/content/full/124/2/255| accessdate = 2007-02-28| pmid = 8534002| doi=10.7326/0003-4819-124-2-199601150-00010}} External links
8 : 1968 births|1991 deaths|AIDS-related deaths in Florida|Burials in Pennsylvania|HIV/AIDS activists|People from Fort Pierce, Florida|People from Tamaqua, Pennsylvania|University of Florida alumni |
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